Results 231 to 240 of about 3,369,116 (395)
A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang+17 more
wiley +1 more source
Managing the Giant: A Novel Approach in Orthotopic Heart Transplantation With Extreme Left Atrial Enlargement. [PDF]
Giovannico L+7 more
europepmc +1 more source
Serotyping for homotransplantation. XXIV. Heart transplantation
Paul I. Terasaki+3 more
openalex +1 more source
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen+18 more
wiley +1 more source
Global challenges and development of heart transplantation: Wuhan Protocol development and clinical implementation. [PDF]
Wang Y, Li F, Qiao W, Zhang J, Dong N.
europepmc +1 more source
Combined heart-lung transplantation for end-stage Eisenmenger’s syndrome
Christopher G.A. McGregor+13 more
openalex +1 more source
ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie+11 more
wiley +1 more source
Acquired Genotype-Positive Long QT Syndrome After Pediatric Heart Transplantation. [PDF]
Barresi NV+3 more
europepmc +1 more source