Results 241 to 250 of about 418,657 (362)

EARLY INFECTIONS IN KIDNEY, HEART, AND LIVER TRANSPLANT RECIPIENTS ON CYCLOSPORINE

, 1983
J. Stephen Dummer, A. M. Hardy, Abbas Poorsattar, Monto Ho   +3 more
openalex   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source

Transforming heart transplantation care with multi-omics insights. [PDF]

J Transl Med
Zou Z, Han J, Zhu Z, Zheng S, Xu X, Liu S.   +5 more
europepmc   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Heart Transplantation in Advanced Heart Failure Due to IgG4-Related Endomyocardial Fibrosis. [PDF]

JACC Case Rep
Burgos LM, Baro Vila RC, Vrancic JM, De Bortoli MA, Malano D, San Martino JA, Diez M.   +6 more
europepmc   +1 more source

Outcomes and predictors of early infection after heart transplantation [PDF]

, 2018
Balsara, Keki, Itoh, Akinobu, Micek, Scott, Shultes, Kendall C, Shuster, Jerrica E, Tellor, Bethany R, Vader, Justin M   +6 more
core   +2 more sources

ACUTE REJECTION AND MASSIVE CYCLOSPORINE REQUIREMENTS IN HEART TRANSPLANT RECIPIENTS TREATED WITH RIFAMPIN

, 1985
DENNIS L. MODDRY, Edward B. Stinson, PHILIP E. DYER, Stuart W. Jamieson, JOHN C. BALDWIN, Norman E. Shumway   +5 more
openalex   +1 more source

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non‐Small Cell Lung Cancer via Hippo Pathway Activation

Advanced Science, EarlyView.
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang, Huayan Xie, Qiang Lin, Liujin Zhou, Junxi Liu, Zekai Fang, Ziling Tang, Ruijie Yuan, Jinxuan Su, Sijia Li, Wenlin Wang, Mingyu Pan, Hao Wang, Xiaoyong Dai, Guocai Wang, Yubo Zhang   +15 more
wiley   +1 more source

PCSK9 inhibitors in the management of hypercholesterolaemia after heart transplantation in the UK, a single centre observational study. [PDF]

Sci Rep
Akhtar W, Khan T, Neves E, Browne C, Tawil M, Lyster H, Dar O.   +6 more
europepmc   +1 more source

Multilineage hematopoietic reconstitution of supralethally irradiated rats by syngeneic whole organ transplantation: with particular reference to the liver [PDF]

, 1996
Demetris, AJ, Murase, N, Rao, AS, Starzl, TE, Thomson, AW, Tsamandas, A, Ye, Q   +6 more
core