Results 41 to 50 of about 1,952,025 (296)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Tricuspid regurgitation influences outcome after heart transplantation
We investigated the correlation between tricuspid regurgitation (TR) and late survival, and its relation to bicaval (BC) and biatrial (BA) technique, after heart transplantation (HTx)
Wartig, Maria +6 more
core +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Heart transplantation in chagas cardiomyopathy
Heart transplantation modifies the natural history of end-stage chronic Chagas cardiomyopathy and is currently established as a valuable therapeutic option.Patients with Chagas disease and heart transplantation require close and multidisciplinary follow ...
Favaloro, Liliana Ethel +1 more
core +1 more source
Oritavancin in LVAD related infections - a chance for shortening therapy and improving outcomes
Background LVAD utility in heart failure patients is growing. Despite advancement in technology rates of LVAD- related infections remain high limiting outcomes. We aimed to assess the effectiveness and safety of oritavancin for LVAD-related Gram-positive
Marta Załęska-Kocięcka +13 more
doaj +1 more source
Ventricular arrhythmias (VA) are of major concern in the field of cell therapy, potentially limiting its safety and efficacy. We sought to investigate the effects of CD34 + cell therapy on VA burden in patients with chronic heart failure (CHF).
Gregor Poglajen +6 more
doaj +1 more source
Panoramic on Epigenetics in Coronary Artery Disease and the Approach of Personalized Medicine
Epigenetic modifications play a fundamental role in the progression of coronary artery disease (CAD). This panoramic review aims to provide an overview of the current understanding of the epigenetic mechanisms involved in CAD pathogenesis and highlights ...
Marcello Bergonzini +13 more
doaj +1 more source
Neonatal heart transplantation [PDF]
Neonatal heart transplantation was developed and established in the 1980's as a durable modality of therapy for complex-uncorrectable heart disease. Patients transplanted in the neonatal period have experienced unparalleled long-term survival, better than for any other form of solid-organ transplantation.
Mohan, John, Leonard L, Bailey
openaire +2 more sources
Identify New Genetic Variants on Chromosome 6 Associated with Mortality after Heart Transplantation
PURPOSE: Graft failure in heart transplant recipients is still the leading cumulative cause of death, rejection related injuries likely being an important contributor.
Nilsson, J., +3 more
core +1 more source

