Results 41 to 50 of about 233,217 (309)

Neonatal heart transplantation [PDF]

Annals of Cardiothoracic Surgery, 2018
Neonatal heart transplantation was developed and established in the 1980's as a durable modality of therapy for complex-uncorrectable heart disease. Patients transplanted in the neonatal period have experienced unparalleled long-term survival, better than for any other form of solid-organ transplantation.
Mohan, John, Leonard L, Bailey
openaire   +2 more sources

Risk factors for Chagas` disease reactivation after heart transplantation

, 2008
Background: Chagas` disease is the illness caused by the protozoan Trypanosoma cruzi and it is still endemic in Latin America. Heart transplantation is a therapeutic option for patients with end-stage Chagas` cardiomyopathy.
BOCCHI, Edimar A., BACAL, Fernando, AMATO NETO, Vicente, STRABELLI, Tania Mara V., CAMPOS, Silvia V., SILVA, Christiano P., STOLF, Noedir Antonio G.   +6 more
core   +1 more source

The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection [PDF]

, 2019
BACKGROUND - Alterations in the partly microbiota-dependent carnitine–γ-butyrobetaine (γBB)–trimethylamine N-oxide (TMAO) pathway have been linked to the progression of heart failure and atherosclerotic disease. We evaluated if circulating γBB, TMAO, and
Gude, Einar, Trøseid, Marius, Hov, Johannes Espolin Roksund, Berge, Rolf Kristian, Karason, Kristjan, Dellgren, Gøran, Gullestad, Lars, Arora, Satish, Mayerhofer, Christiane Caroline, Ueland, Thor, Andreassen, Arne K., Broch, Kaspar, Aukrust, Pål, Svardal, Asbjørn M.   +13 more
core   +1 more source

Clinical Outcomes and Effectiveness of Heart Transplantation in Patients With Systemic Light-chain Cardiac Amyloidosis

, 2022
Background: In systemic light-chain (AL) amyloidosis, cardiac involvement is a major determinant of survival; however, cardiac response is limited even after systemic treatment in a majority of patients, and some require heart transplantation ...
Sang Eun Lee, Hyo-In Choi, Hyehyun Jeong, Miyoung Kim, Tae-Jin Yun, Jae Won Lee, Chan Sik Park, Dok Hyun Yoon, Heounjeong Go, Sung-Ho Jung, Jae-Joong Kim, Inhwan Hwang, Jwa Hoon Kim, Jeong-Jun Park, Min-Seok Kim, Hyungwoo Cho   +15 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Heart-lung transplantation for idiopathic pulmonary arterial hypertension and giant pulmonary artery aneurysm – case report

Journal of Cardiothoracic Surgery, 2020
Backgound Idiopathic pulmonary arterial hypertension (IPAH) is a rare condition that requires lung transplantation in patients’ refractory to medical therapy.
T. Eadington, K. Santhanakrishnan, R. Venkateswaran   +2 more
doaj   +1 more source

The Choice of Tactics for Surgical Treatment of Acute De Bakey Type I Aortic Dissection in a Multidisciplinary Surgical Hospital

Неотложная медицинская помощь, 2023
BACKGROUND Acute proximal aortic dissection (Stanford type A) remains the most common fatal pathology of the thoracic aorta. Despite the improvement of surgical technologies, hospital mortality after emergency surgical interventions is 17–25%, in ...
A. V. Redkoborody, V. S. Selyaev, N. V. Rubtsov, L. S. Kokov, R. Sh. Muslimov, I. E. Popova, K. M. Torshkhoyev, L. G. Khutsishvili   +7 more
doaj   +1 more source

Right-to-left Shunt Through a Patent Foramen Ovale Left Open in the Management of Acute Right Heart Failure After Heart Transplantation

, 2008
Severe pulmonary hypertension is a risk factor for mortality in heart transplantation due to elevated post-operative right heart failure. Various treatment modalities have been used in the management of pulmonary hypertension in the peri-operative period.
Buyukates, Mustafa, KULA, SERDAR, İRİZ, ERKAN, OKTAR, GÜRSEL LEVENT, ERER, DİLEK, ÖZDOĞAN, MEHMET   +5 more
core   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

Arthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of the SPRING Italian Registry Collaborators   +77 more
wiley   +1 more source

Induction with anti-thymocyte globulin in heart transplantation is associated with better long-term survival compared with basiliximab

, 2015
The use of induction therapy may reduce the risk of acute rejection after heart transplantation. This study assessed the association between basiliximab (BAS) vs anti-thymocyte globulin (ATG) induction and long-term survival after heart ...
Nilsson, Johan,, Ansari, David,, Stehlik, Josef, Andersson, Bodil,, Lund, Lars H, Edwards, Leah, Lund University., Höglund, Peter,   +7 more
core   +1 more source