Results 101 to 110 of about 423,998 (313)

Modelling mitral valvular dynamics–current trend and future directions [PDF]

, 2017
Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment ...
Berry, Colin, Danton, Mark, Feng, Liuyang, Gao, Hao, Luo, Xiaoyu, Ma, Xingshuan, Qi, Nan   +6 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

In Vitro Flow Modelling for Mitral Valve Leakage Quantification [PDF]

, 2009
In this study particle image velocimetry (PIV) is used to measure and visualise the blood flow through a leaking mitral heart valve. The results are compared with the results from Doppler echocardiography and computational fluid dynamics (CFD). Using CAD,
Claessens, Tom, Kaminsky, Radoslav, Segers, Patrick, Van Der Smissen, Benjamin, Van Ransbeeck, Peter, Verdonck, Pascal, Vermeulen, Mathias   +6 more
core   +1 more source

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source

Injectable living marrow stromal cell-based autologous tissue engineered heart valves: first experiences with a one-step intervention in primates [PDF]

, 2017
Aims A living heart valve with regeneration capacity based on autologous cells and minimally invasive implantation technology would represent a substantial improvement upon contemporary heart valve prostheses.
Agarkova, Irina, Baumgartner, Laura, Black, Melanie, Bracher, Mona, Brokopp, Chad, Emmert, Maximilian Y., Falk, Volkmar, Franz, Thomas, Gruenenfelder, Juerg, Hoerstrup, Simon P., Kortsmit, Jeroen, Scherman, Jacques, Schoenauer, Roman, Verbeek, Renier, Weber, Benedikt, Wolint, Petra, Zilla, Peter, Zund, Gregor   +17 more
core  

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Transcatheter pulmonary valve replacement with the venusP-valve system in a patient with double outlet right ventricle and transposition of the great arteries a first-in-human case report

Frontiers in Cardiovascular Medicine
The Taussig-Bing anomaly is a rare form of double outlet right ventricle (DORV) characterized by complex physiology, often requiring multiple surgeries.
Federica Gramegna, Paolo Denti, Matteo Saccocci, Nicola Buzzatti, Alessandro Faggi, Eustachio Agricola, Eustachio Agricola, Ottavio Alfieri, Ottavio Alfieri, Massimo Chessa, Francesco Maisano, Francesco Maisano   +11 more
doaj   +1 more source

Nehéz helyzetben a HEART Team: valve-in-valve implantáció? = HEART Team in trouble: valve-in-valve implantation? [PDF]

, 2018
L
Balogh, Ágnes, Bódi, Annamária, Csanádi, Zoltán, Jenei, Csaba, Kertész, Attila Béla, Kracskó, Bertalan, Rácz, Ildikó, Szerafin, Tamás, Szokol, Miklós, Vajda, Csaba, Vajda, Gusztáv   +10 more
core   +2 more sources

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

Generic, simple risk stratification model for heart valve surgery [PDF]

, 2005
BACKGROUND: Heart valve surgery has an associated in-hospital mortality rate of 4% to 8%. This study aims to develop a simple risk model to predict the risk of in-hospital mortality for patients undergoing heart valve surgery to provide information to ...
Ambler, G, Keogh, BE, Kinsman, R, Omar, RZ, Royston, P, Taylor, KM   +5 more
core