Results 11 to 20 of about 192,739 (195)

A Case Report of Acute Heart Failure Due to Infective Aortic Endocarditis Diagnosed by Point-of-care Ultrasound [PDF]

, 2020
Introduction: Infective endocarditis (IE) is a life-threatening condition with significant morbidity and mortality, and can require surgical repair.Case Report: A 36-year-old man presented to the emergency department for worsening dyspnea and chest pain.
Gallagher, Ryan, Hite, Pamela, Jackson, Bradley, Wilson, Michelle   +3 more
core  

Immune Privilege of Heart Valves [PDF]

Frontiers in Immunology, 2021
Immune privilege is an evolutionary adaptation that protects vital tissues with limited regenerative capacity from collateral damage by the immune response. Classical examples include the anterior chamber of the eye and the brain. More recently, the placenta, testes and articular cartilage were found to have similar immune privilege.
Satish N. Nadig, Minoo N. Kavarana, Jennie H. Kwon, Brielle Gerry, William A. Hardy, Olivia Agata Walkowiak, T. Konrad Rajab, Morgan Ashley Hill   +7 more
openaire   +4 more sources

Transcatheter Valve-in-Valve and Valve-in-Ring for Treating Aortic and Mitral Surgical Prosthetic Dysfunction [PDF]

, 2015
Bioprosthetic valve use has increased significantly. Considering their limited durability, there will remain an ongoing clinical need for repairing or replacing these prostheses in the future. The current standard of care for treating bioprosthetic valve
Del Trigo, Maria, Paradis, Jean-Michel, Puri, Rishi, Rodés-Cabau, Josep   +3 more
core   +1 more source

Prosthetic Heart Valves

International Journal of Clinical Practice, 2014
Heart valve replacements improve symptoms and life expectancy but may have potential problems. Biological replacements have limited durability but do not require anticoagulation and are usually used for the relatively elderly. Mechanical valves have a virtually zero primary failure rate but require anticoagulation and are usually used for the ...
openaire   +3 more sources

Standards for heart valve surgery in a ‘Heart Valve Centre of Excellence’ [PDF]

Open Heart, 2015
Surgical centres of excellence should include multidisciplinary teams with specialist expertise in imaging, clinical assessment and surgery for patients with heart valve disease. There should be structured training programmes for the staff involved in the periprocedural care of the patient and these should be overseen by national or international ...
Philippe Pibarot, Mario Petrou, Raphael Rosenhek, Brian Campbell, Tim Graham, Thoralf M. Sundt, Catherine M Otto, Carlos A. Mestres, Bernard Prendergast, Jeremy Tinkler, Christa Gohlke-Bärwolf, Donna Greenhalgh, Simon Ray, John C. Chambers   +13 more
openaire   +3 more sources

Bridging aortic valve surgery to 21st century. what can a surgeon do [PDF]

, 2019
Aortic valve stenosis is the most clinically relevant valvular heart disease in the elderlies. Surgical aortic valve replacement (SAVR) represented, for decades, the standard of care for the treatment of severe aortic stenosis.
Barretta, Antonio, Biondi-Zoccai, Giuseppe, D��Abramo, Mizar, Ferrante, Luisa, Frati, Giacomo, Greco, Ernesto, Guerrera, Manuel, Iaccarino, Alessandra, Marullo, Antonino, Miraldi, Fabio, Peruzzi, Mariangela, Proietti, Piero, Saade, Wael, Sciarretta, Sebastiano   +13 more
core   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field [PDF]

, 2006
A hallmark of heart-valve development is the swelling and deposition of extracellular matrix in the heart-valve region. Only myocardium overlying this region can signal to underlying endothelium and cause it to lose cell–cell contacts, delaminate, and ...
Rivera-Feliciano, José, Tabin, Clifford J.   +1 more
core   +1 more source

The Endocardium and Heart Valves

Cold Spring Harbor Perspectives in Biology, 2020
Endocardial cells are specialized endothelial cells that, during embryogenesis, form a lining on the inside of the developing heart, which is maintained throughout life. Endocardial cells are an essential source for several lineages of the cardiovascular system including coronary endothelium, endocardial cushion mesenchyme, cardiomyocytes, mural cells,
Bailey K Dye, Joy Lincoln
openaire   +4 more sources

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source