Results 21 to 30 of about 2,810,461 (415)

Macrophage lineages in heart valve development and disease.

open access: yesCardiovascular Research, 2020
Heterogeneous macrophage lineages are present in the aortic and mitral valves of the heart during development and disease. These populations include resident macrophages of embryonic origins and recruited monocyte-derived macrophages prevalent in disease.
A. J. Kim, Na Xu, K. Yutzey
semanticscholar   +1 more source

Natural history observations in moderate aortic stenosis

open access: yesBMC Cardiovascular Disorders, 2021
Background The natural history of patients with moderate aortic stenosis (AS) is poorly understood. We aimed to determine the long-term outcomes of patients with moderate AS.
Yu Du   +15 more
doaj   +1 more source

A geometrically adaptable heart valve replacement

open access: yesScience Translational Medicine, 2020
A biomimetic prosthetic heart valve is geometrically adaptable to accommodate somatic growth and structural asymmetries within the hearts of sheep.
Sophie C. Hofferberth   +14 more
semanticscholar   +1 more source

Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Strain in Patients With Significant Aortic Stenosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundIn aortic stenosis (AS), symptoms and left ventricular (LV) dysfunction represent a later disease state, and objective parameters that identify incipient LV dysfunction are needed.
Andrew Goodman   +9 more
doaj   +1 more source

Correlations between geomagnetic field and global occurrence of cardiovascular diseases: evidence from 204 territories in different latitude

open access: yesBMC Public Health, 2023
Background The correlation between stable geomagnetic fields and unstable geomagnetic activities with mortality, incidence, and prevalence of cardiovascular diseases (CVDs) remains ambiguous.
Zheng Chai   +4 more
doaj   +1 more source

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart [PDF]

open access: yes, 2009
Heart valve anomalies are some of the most common congenital heart defects, yet neither the genetic nor the epigenetic forces guiding heart valve development are well understood.
A. C Oates   +60 more
core   +3 more sources

Outcomes in Asymptomatic Severe Aortic Stenosis With Preserved Ejection Fraction Undergoing Rest and Treadmill Stress Echocardiography

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundIn asymptomatic patients with severe aortic stenosis and preserved left ventricular ejection fraction, we sought to assess the incremental prognostic value of resting valvuloarterial impedence (Zva) and left ventricular global longitudinal ...
Chetan P. Huded   +11 more
doaj   +1 more source

Design and Fabrication of Three-Dimensional Scaffolds for Tissue Engineering of Human Heart Valves [PDF]

open access: yes, 2009
We developed a new fabrication technique for 3-dimensional scaffolds for tissue engineering of human heart valve tissue. A human aortic homograft was scanned with an X-ray computer tomograph.
Fu, P.   +8 more
core   +1 more source

Relationship Between the Ratio of Acceleration Time/Ejection Time and Mortality in Patients With High‐Gradient Severe Aortic Stenosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The ratio of acceleration time/ejection time (AT/ET) is a simple and reproducible echocardiographic parameter that integrates aortic stenosis severity and its consequences on the left ventricle.
Alexandre Altes   +10 more
doaj   +1 more source

Dynamic Views of Structure and Function during Heart Morphogenesis [PDF]

open access: yes, 2006
Congenital heart defects remain the most common birth defect in humans, occurring in over 1% of live births. The high prevalence of cardiac malformations can be partially attributed to limited knowledge regarding the embryonic roots of the disease.
Forouhar, Arian Soroush
core   +1 more source

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