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Heart Valve Regeneration

2005
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the diseased tissue by mechanical or bioprosthetic valve substitutes in order to avoid potentially fatal cardiac or systemic consequences.
Frederick J. Schoen   +2 more
openaire   +2 more sources

Prosthetic Heart Valves

New England Journal of Medicine, 1996
Since the 1950s more than 80 models of prosthetic heart valves have been developed and used. More than 60,000 valve replacements are performed annually in the United States. Prosthetic heart valves may be mechanical or bioprosthetic. Mechanical valves, which are composed primarily of metal or carbon alloys, are classified according to their structure ...
Wanpen Vongpatanasin   +2 more
openaire   +3 more sources

Transplantability of Heart Valves

Archives of Surgery, 1962
The majority of unresolved problems in the present era of heart surgery are biologic rather than technical. The advances made in total body perfusion, the improvement in the protection of the myocardium in artificially induced cardiac arrest, etc., have made it possible to deal quite successfully with several types of congenital and acquired heart ...
Francis Robicsek   +3 more
openaire   +3 more sources

The collagen of heart valve

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1977
A hydroxylysine-rich type I collagen has been isolated from pepsin-digested porcine heart valve. The ratio of alpha1 to alpha2 in the isolated molecule was 2:1. The component alpha chains exhibited unusual chromatographic behavior in comparison to corresponding chains from human dermis and lathyritic rat skin collagen.
David Collins   +3 more
openaire   +2 more sources

Heart valve surgery

Current Opinion in Cardiology, 1993
Progress in valve repair and replacement continued over the past year. Aortic valve repair for aortic insufficiency appears promising, and aortic decalcification may still be a useful alternative in certain cases of aortic stenosis. Mitral valve repair, well accepted for myxomatous valves, presents a challenge in ischemic disease.
Christopher M. Feindel, Tirone E. David
openaire   +3 more sources

Heart valve tissue engineering: an overview of heart valve decellularization processes.

Regenerative medicine, 2018
Despite recent advances in medicine and surgery, many people still suffer from cardiovascular diseases, which affect their life span and morbidity. Regenerative medicine and tissue engineering are novel approaches based on restoring or replacing injured ...
Safieh Boroumand   +4 more
semanticscholar   +1 more source

Heart valves

2012
Publisher Summary A prosthetic heart valve is a medical device that replaces a diseased native valve and that enables blood flow in the cardiac chambers to be regulated. A mechanical valve consists of an occluder, an occluder retention mechanism, and a sewing cuff. A typical tissue valve consists of porcine or bovine tissue, a stent, and a sewing cuff.
openaire   +2 more sources

Heart Valve Disease [PDF]

open access: possible, 2009
This chapter was designed to provide the reader with a brief overview of the current surgical treatment options for heart valve disease. Major topics of discussion are: (1) development of prosthetic valve replacements; (2) current issues with valve replacement; (3) major valvular diseases that affect humans in the Western world; and (4) recent advances
Ranjit John, Kenneth Liao
openaire   +1 more source

Prosthetic heart valves

Surgery (Oxford), 2007
Abstract The number of heart valve replacement procedures has increased over the past four decades, with >200,000 done worldwide every year. Various valve substitutes are available, and are broadly divided into biological and mechanical prostheses. Choice is dictated by multiple factors, including longevity of the valve substitute as well as patient ...
Yasir Abu-Omar   +3 more
openaire   +2 more sources

Choosing A Prosthetic Heart Valve

Cardiology Clinics, 1991
Although most of the available prosthetic heart valves function remarkably well, the variety of available choices attests to the inability of any single one to fulfill the requirements of the ideal valve substitute. The mechanical prostheses include the caged-ball, tilting-disc, and bileaflet valves. Tissue valves available in the United States are the
Michael H. Crawford, Jorge A. Wernly
openaire   +4 more sources

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