We have developed a unique method for pre‐clinical heart valve prostheses evaluation of calcification propensity. Results from the test can directly be translated into improvements of prostheses design, materials, and anti‐calcification treatments, and therefore have a significant impact on heart valve prostheses quality and patient care in the future.
Nicole Kiesendahl +6 more
wiley +1 more source
Trial‐Based Hemolysis Modeling to Investigate Operating Modes of Continuous‐Flow LVADs
This work presents a methodology for determining online‐capable hemolysis models for continuous‐flow LVADs, derived from in vitro trials. The models are based on fitting a modified power law and applying the Lagrangian approach. They assist clinicians in selecting treatment strategies that minimize hemolysis, as demonstrated with the Sputnik1 LVAD ...
Patrick Borchers +2 more
wiley +1 more source
Evaluation of TTK Chitra heart valve prosthesis in pediatric patients. [PDF]
Varma PK +3 more
europepmc +1 more source
Initial experience of a large, self-expanding, and fully recapturable transcatheter aortic valve: The UK & Ireland Implanters' registry. [PDF]
OBJECTIVES: The UK & Ireland Implanters' registry is a multicenter registry which reports on real-world experience with novel transcatheter heart valves. BACKGROUND: The 34 mm Evolut R transcatheter aortic valve is a self-expanding and fully recapturable
Abdelaziz, HK +49 more
core +1 more source
In Vitro Calcification Evaluation of Polycarbonate Urethane—Impact of Production Processes
The study shows that hot pressing induces chemical changes in PCU, promoting calcification, while solution‐cast patches remain unaffected. ABSTRACT Background Heart valve diseases remain a leading cause of death in industrialized nations. Polycarbonate urethane (PCU) is a promising material for heart valve prostheses due to its biocompatibility and low
Jan Ritter +8 more
wiley +1 more source
First Ex Vivo Animal Study of a Biological Heart Valve Prosthesis Sensorized with Intravalvular Impedance. [PDF]
Cercenelli L +3 more
europepmc +1 more source
Hydraulic In Vitro Characterization of MR‐Conditional Blood Pumps
Cardiac surgery in neonates requires close placement of cardiopulmonary bypass machines due to limited blood volume, complicating MR compatibility. This study introduces three MR‐conditional blood pump prototypes. None interfered with MRI imaging, though RF‐related sensor effects remain untested.
Dominik T. Schulte +6 more
wiley +1 more source
Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov +11 more
wiley +1 more source
Large Animal Models for Transcatheter Heart Valve Prosthesis Development: Making Sheep's Eyes at Supra-Annular Banding. [PDF]
Modine T, Ben Ali W, Perrin N.
europepmc +1 more source
Prognostic value of the ratio between prothesis area and indexed annulus area measured by multiSlice-CT for transcatheter aortic valve implantation procedures [PDF]
Background Postprocedural aortic regurgitations following transcatheter aortic valve implantation (TAVI) procedures remain an is- sue. Benefit of oversizing strategies to prevent them isn’t well established.
Bical A +8 more
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