Results 91 to 100 of about 2,650,139 (381)

Materials and manufacturing perspectives in engineering heart valves: a review

open access: yesMaterials Today Bio, 2020
Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves.
F. Oveissi   +4 more
doaj  

Dynamic Echocardiographic Imaging of a Valve-in-Valve Mitral Prosthesis

open access: yesCase Reports in Radiology, 2022
Dynamic imaging of heart valves and specifically prosthetic valves is a central benefit of echocardiography. Most bioprosthetic heart valves degenerate over a given time and hence require repeat valve replacement which carries a significant risk of ...
Bishoy Wassef   +4 more
doaj   +1 more source

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

Análise do estudo anatomopatológico de pacientes submetidos a cirurgia valvar no InCór - HC FMUSP Anatomopathological study of patients submitted to valvar surgery at InCór-HC FMUSP

open access: yesBrazilian Journal of Cardiovascular Surgery, 1992
Das 44 necropsias realizadas em pacientes submetidos a cirurgia valvar no ano de 1990 no InCór, foram encontradas como causas clínicas de óbito nos pacientes mitrais: coagulopatia e sangramento em 11 casos; baixo débito em 7; choque cardiogênico em 5 ...
Hélio A Fabri   +8 more
doaj  

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

Mechanistic Insights into Bioprosthetic Heart Valve Calcification and Anti-Calcification Strategies

open access: yesReviews in Cardiovascular Medicine
Prosthetic heart valves are crucial for treating valvular heart disease and serve as substitutes for native valves. Bioprosthetic heart valves (BHVs) are currently the most common type used in clinical practice.
Yuxiao Yang, Limin Lan, Yi Lin
doaj   +1 more source

Bioinspired polymeric heart valves: A combined in vitro and in silico approachCentral MessagePerspective

open access: yesJTCVS Open, 2023
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD   +10 more
doaj  

Multiple-Step Injection Molding for Fibrin-Based Tissue-Engineered Heart Valves

open access: yesTissue Engineering. Part C, Methods, 2015
Heart valves are elaborate and highly heterogeneous structures of the circulatory system. Despite the well accepted relationship between the structural and mechanical anisotropy and the optimal function of the valves, most approaches to create tissue ...
Miriam Weber   +8 more
semanticscholar   +1 more source

Combination of Polydopamine and Plasma Oxidation to Increase Tissue Integration of Polyurethane‐Silicone Copolymers for Cardiovascular Implants

open access: yesAdvanced Healthcare Materials, EarlyView.
Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong   +5 more
wiley   +1 more source

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