Results 21 to 30 of about 2,830,227 (287)

Hybrid heart valves with VEGF-loaded zwitterionic hydrogel coating for improved anti-calcification and re-endothelialization

open access: yesMaterials Today Bio, 2022
With the aging of the population in worldwide, valvular heart disease has become one of the most prominent life-threatening diseases in human health, and heart valve replacement surgery is one of the therapeutic methods for valvular heart disease ...
Qi Tong   +6 more
doaj   +1 more source

Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves.

open access: yesEuropean Heart Journal, 2019
AIMS The pathogenesis of endocarditis is not well understood resulting in unsuccessful attempts at prevention. Clinical observations suggest that Staphylococcus aureus infects either damaged or inflamed heart valves.
L. Liesenborghs   +15 more
semanticscholar   +1 more source

Clinical performance of decellularized heart valves versus standard tissue conduits: a systematic review and meta-analysis

open access: yesJournal of Cardiothoracic Surgery, 2020
Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi   +4 more
doaj   +1 more source

Bioinspired polymeric heart valves: A combined in vitro and in silico approachCentral MessagePerspective

open access: yesJTCVS Open, 2023
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD   +10 more
doaj   +1 more source

Bioprosthetic Heart Valves: Upgrading a 50-Year Old Technology

open access: yesFrontiers in Cardiovascular Medicine, 2019
Prosthetic heart valves have been commonly used to address the increasing prevalence of valvular heart disease. The ideal prosthetic heart valve substitute should closely mimic the characteristics of a normal native heart valve.
Kan Li
semanticscholar   +1 more source

Recent progress in biomaterials for heart valve replacement: Structure, function, and biomimetic design

open access: yesView, 2021
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao   +10 more
doaj   +1 more source

Modern view on calcification of xenogenic bioprosthetic heart valves and their anti-calcification treatment strategies

open access: yesТрансплантология (Москва), 2023
Aim. The aim of this review was to analyze publications describing studies focusing on the pathophysiological mechanisms of calcification of bioprosthetic heart valves, and to substantiate new and promising methods of calcification prevention for the ...
A. E. Kostyunin   +3 more
doaj   +1 more source

HEART VALVE SURGERY

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 1965
SUMMARY This paper summarizes the experience in the treatment of a series of 1,370 cases of open-heart surgery. Of these, 964 valvular lesions and the associated pathologic lesion are analyzed. Details of correction and immediate and late results in the treatment of the following groups of lesions were studied: 74 cases of congenital aortic stenosis ...
E J, ZERBINI   +2 more
openaire   +2 more sources

Anticoagulation for pregnant women with mechanical heart valves: a systematic review and meta-analysis

open access: yesEuropean Heart Journal, 2017
Aims To review maternal and foetal outcomes in women with mechanical heart valves (MHVs) treated with vitamin-K antagonists (VKAs), first-trimester heparin followed by VKAs (sequential treatment), low molecular weight heparin (LMWH) and unfractionated ...
R. D’Souza   +7 more
semanticscholar   +1 more source

Evaluation of pliable bioresorbable, elastomeric aortic valve prostheses in sheep during 12 months post implantation

open access: yesCommunications Biology, 2023
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis   +14 more
doaj   +1 more source

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