Results 21 to 30 of about 2,697,360 (401)

Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy

open access: yesApplied Mechanics, 2023
The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds ...
Sahar Khan, Faiz Syed, Milan Toma
doaj   +1 more source

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart [PDF]

open access: yes, 2009
Heart valve anomalies are some of the most common congenital heart defects, yet neither the genetic nor the epigenetic forces guiding heart valve development are well understood.
A. C Oates   +60 more
core   +5 more sources

Multimodality imaging in the diagnostic approach to a patient with carcinoid heart disease involving four heart valves

open access: yesClinical Case Reports, 2022
Carcinoid heart disease is a rare condition that occurs in less than half of patients with carcinoid syndrome. The disease mainly affects right‐sided heart valves; however, in 5%–10%, it can also involve left‐sided valves.
Shirin Habibi Khorasani   +6 more
doaj   +1 more source

Hybrid heart valves with VEGF-loaded zwitterionic hydrogel coating for improved anti-calcification and re-endothelialization

open access: yesMaterials Today Bio, 2022
With the aging of the population in worldwide, valvular heart disease has become one of the most prominent life-threatening diseases in human health, and heart valve replacement surgery is one of the therapeutic methods for valvular heart disease ...
Qi Tong   +6 more
doaj   +1 more source

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves. [PDF]

open access: yes, 2015
The mesenchymal cushions lining the early embryonic heart undergo complex remodelling to form the membranous ventricular septum as well as the atrioventricular and semilunar valves in later life.
Andrews, WD   +3 more
core   +1 more source

Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]

open access: yes, 2015
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core   +8 more sources

21 Tesla MRI Microimaging of Rat Heart by Superparamagnetic Antimyoglobin Bound Nanoparticles [PDF]

open access: yes, 2008
Superparamagnetic iron-oxide bound antimyoglobin (SPIOM) characteristics were analyzed at different pH. After injecting SPIOM in heart, ex vivo magnetic resonance microimaging (MRM) technique was used to visualize microvasculature of rat heart including
Rakesh Sharma
core   +2 more sources

Materials and manufacturing perspectives in engineering heart valves: a review

open access: yesMaterials Today Bio, 2020
Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves.
F. Oveissi   +4 more
doaj   +1 more source

Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves.

open access: yesEuropean Heart Journal, 2019
AIMS The pathogenesis of endocarditis is not well understood resulting in unsuccessful attempts at prevention. Clinical observations suggest that Staphylococcus aureus infects either damaged or inflamed heart valves.
L. Liesenborghs   +15 more
semanticscholar   +1 more source

Bioinspired polymeric heart valves: A combined in vitro and in silico approachCentral MessagePerspective

open access: yesJTCVS Open, 2023
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD   +10 more
doaj   +1 more source

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