Results 21 to 30 of about 89,308 (311)

Recent progress in biomaterials for heart valve replacement: Structure, function, and biomimetic design

View, 2021
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao, Tingting Tao, Hongfei Xu, Cen Chen, In‐Seop Lee, Sungmin Chung, Zhihui Dong, Weidong Li, Liang Ma, Hao Bai, Qianming Chen   +10 more
doaj   +1 more source

Bioinspired polymeric heart valves: A combined in vitro and in silico approachCentral MessagePerspective

JTCVS Open, 2023
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD, Xinying Liu, PhD, Jacopo Emilio Giaretta, PhD, Thanh Phuong Hoang, Matthew Crago, BE, Syamak Farajikhah, PhD, Luke Mosse, PhD, David Frederick Fletcher, PhD, Fariba Dehghani, PhD, David Scott Winlaw, MD, Sina Naficy, PhD   +10 more
doaj   +1 more source

Modern view on calcification of xenogenic bioprosthetic heart valves and their anti-calcification treatment strategies

Трансплантология (Москва), 2023
Aim. The aim of this review was to analyze publications describing studies focusing on the pathophysiological mechanisms of calcification of bioprosthetic heart valves, and to substantiate new and promising methods of calcification prevention for the ...
A. E. Kostyunin, T. V. Glushkova, A. N. Stasev, E. A. Ovcharenko   +3 more
doaj   +1 more source

Substituição valvar por valva aórtica homóloga montada em suporte e preservada pelo glutaraldeído: estudo multicêntrico Valvar replacement with a glutaraldehyde preserved stent-mounted homologous aortic valve: a multicenter study

Brazilian Journal of Cardiovascular Surgery, 1988
A substituição valvar por valva aórtica homóloga montada em suporte flexível e preservada pelo glutaraldeído é procedimento original e informações preliminares já foram relatadas anteriormente.
Ênio Buffolo, Cláudio A Salles, José Vanderley Neto, José Telles de Mendonça, Ivan S. Joviano Casagrande, José Carlos S Andrade, Honório Palma   +6 more
doaj   +1 more source

Evaluation of pliable bioresorbable, elastomeric aortic valve prostheses in sheep during 12 months post implantation

Communications Biology, 2023
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis, Bente J. de Kort, Wojciech Szymczyk, Jan Willem van Rijswijk, Sylvia Dekker, Rob Driessen, Niels Wijkstra, Paul F. Gründeman, Hans W. M. Niessen, Henk M. Janssen, Serge H. M. Söntjens, Patricia Y. W. Dankers, Anthal I. P. M. Smits, Carlijn V. C. Bouten, Jolanda Kluin   +14 more
doaj   +1 more source

Echocardiography Aided by Computed Tomography to Diagnose Obstructive Masses in Patients with Prosthetic Heart Valves

, 2020
To the Editor: We appreciate Kealhofer and colleagues’ report on their beneficial use of cardiac computed tomography (CT) for evaluating prosthetic aortic valve dysfunction.1 We want to contribute further by drawing attention to the role of cardiac CT in
Güner, Ahmet, Özkan, Mehmet, Kalçık, Macit, Gündüz, Sabahattin   +3 more
core   +1 more source

Fatores de risco em operações valvares: análise de 412 casos

Brazilian Journal of Cardiovascular Surgery, 1997
O tratamento cirúrgico das valvopatias é muito freqüente e sua mortalidade ainda não se aproxima de zero. Neste estudo, procuramos identificar diversos fatores que poderiam aumentar o risco cirúrgico nestes procedimentos.
Ronaldo Machado BUENO, Vicente ÁVILA NETO, Ricardo F. A. MELO   +2 more
doaj   +1 more source

Optimization of anticoagulant therapy in patients undergoing mechanical heart valve replacement

Фундаментальная и клиническая медицина, 2023
Acquired heart defects have a high prevalence among patients of different age groups and represent a significant social problem. To date, surgery remains the only effective option to treat acquired heart disease, and replacement of the dysfunctional ...
S. A. Tkachenko, D. A. Astapov, A. V. Bogachev-Prokofiev, A. S. Zalesov, A. N. Pivkin, A. G. Makaev, Kh. A. Agaeva, R. M. Sharifulin   +7 more
doaj   +1 more source

Standards for heart valve surgery in a ‘Heart Valve Centre of Excellence’ [PDF]

Open Heart, 2015
Surgical centres of excellence should include multidisciplinary teams with specialist expertise in imaging, clinical assessment and surgery for patients with heart valve disease. There should be structured training programmes for the staff involved in the periprocedural care of the patient and these should be overseen by national or international ...
Chambers, John, Ray, Simon, Prendergast, Bernard, Graham, Tim, Campbell, Brian, Greenhalgh, Donna, Petrou, Mario, Tinkler, Jeremy, Gohlke-Bärwolf, Christa, Mestres, Carlos A, Rosenhek, Raphael, Pibarot, Philippe, Otto, Catherine, Sundt, Thoralf   +13 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source