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Materials and manufacturing perspectives in engineering heart valves: a review
Valvular heart diseases (VHD) are a major health burden, affecting millions of people worldwide. The treatments for such diseases rely on medicine, valve repair, and artificial heart valves including mechanical and bioprosthetic valves.
F. Oveissi +4 more
doaj +1 more source
Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core +8 more sources
Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi +4 more
doaj +1 more source
Background: Polymeric heart valves (PHVs) may address the limitations of mechanical and tissue valves in the treatment of valvular heart disease. In this study, a bioinspired valve was designed, assessed in silico, and validated by an in vitro model to ...
Aeryne Lee, PhD +10 more
doaj +1 more source
SUMMARY This paper summarizes the experience in the treatment of a series of 1,370 cases of open-heart surgery. Of these, 964 valvular lesions and the associated pathologic lesion are analyzed. Details of correction and immediate and late results in the treatment of the following groups of lesions were studied: 74 cases of congenital aortic stenosis ...
E J, ZERBINI +2 more
openaire +2 more sources
Aim. The aim of this review was to analyze publications describing studies focusing on the pathophysiological mechanisms of calcification of bioprosthetic heart valves, and to substantiate new and promising methods of calcification prevention for the ...
A. E. Kostyunin +3 more
doaj +1 more source
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao +10 more
doaj +1 more source
Carcinoid Heart Disease: Early Outcomes after Surgical Valve Replacement in Nine Patients [PDF]
Aim: To describe the early outcomes of carcinoid patients undergoing surgical heart valve replacement. Methods: In a retrospective study, records of patients with symptomatic carcinoid heart disease referred for valve surgery between 2012 and 2016 ...
Clark, Stephen, Mujtaba, Syed Saleem
core +2 more sources
A substituição valvar por valva aórtica homóloga montada em suporte flexível e preservada pelo glutaraldeído é procedimento original e informações preliminares já foram relatadas anteriormente.
Ênio Buffolo +6 more
doaj +1 more source
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis +14 more
doaj +1 more source

