Results 101 to 110 of about 1,497,170 (197)

An intelligent nanoreservoir system promotes heart valve regeneration via ROS scavenging and immunomodulation

Bioactive Materials
In situ regeneration of tissue-engineered heart valves (TEHV) is a promising strategy to overcome the limitations of existing heart valve prostheses. Although, decellularized aortic valves (DAVs) are widely regarded as a scaffold in the construction of ...
Pengning Fan, Yuqi Liu, Xingyu Qian, Jinsheng Li, Yin Xu, Xiang Qiu, Lu Tong, Fuqiang Tong, Zhengfeng Fan, Yidan Zheng, Hanshen Luo, Teng Zeng, Yunbing Wang, Li Xu, Fei Li   +14 more
doaj   +1 more source

Purinergic ecto-enzymes in human and ovine aortic valves: indicators of bacterial nanocellulose scaffold cellularization

Artificial Cells, Nanomedicine, and Biotechnology
Purinergic signalling pathways play a vital role in the biological functions of the aortic valve (AV) through nucleotide and adenosine-dependent receptor effects.
Barbara Kutryb-Zając, Ada Kawecka, Gabriela Harasim, Michał Bieńkowski, Klaudia Stawarska, Krzysztof Urbanowicz, Ryszard T. Smoleński, Maciej M. Kowalik, Magdalena Kołaczkowska, Piotr Siondalski   +9 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Tratamento cirúrgico das valvopatias: parte 1 Valvopathies: surgical treatment. Part 1

Brazilian Journal of Cardiovascular Surgery, 1994
Este assunto, de amplo aspecto, será abordado em três partes. O presente trabalho trata-se do histórico, indicação cirúrgica, conduta pré-operatória e próteses valvulares cardíacas.
Domingo M. Braile, Marco A Volpe, Serginando L Ramin, Dorotéia R. S Souza   +3 more
doaj  

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

Advanced Materials, Volume 38, Issue 55, 1 October 2026.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko, Chiamaka Akah, Ravinder Dahiya   +2 more
wiley   +1 more source

Multi-scale modelling of textile reinforced artificial tubular aortic heart valves

, 2016
Tissue engineered heart valves equivalent to the native aortic heart valves are in development as an alternative to available prostheses. To achieve sufficient mechanical stiffness for application in tissue engineered valves exposed to the systemic ...
Jockenhoevel, Stefan, Sodhani, Deepanshu, Stapleton, Scott E., Moreira, Ricardo, Mela, Petra, Jockenhövel, Stefan, Reese, Stefanie, Jockenhoevel, Stefan; id_orcid   +7 more
core   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Fluid-structure interaction simulation of mechanical aortic valves: a narrative review exploring its role in total product life cycle

Frontiers in Medical Technology
Over the last years computer modelling and simulation has emerged as an effective tool to support the total product life cycle of cardiovascular devices, particularly in the device preclinical evaluation and post-market assessment.
Mariachiara Arminio, Dario Carbonaro, Umberto Morbiducci, Diego Gallo, Claudio Chiastra   +4 more
doaj   +1 more source

Polymeric heart valves: new materials, emerging hopes

, 2009
Heart valve (HV) replacements are among the most widely used cardiovascular devices and are in rising demand. Currently, clinically available devices are restricted to slightly modified mechanical and bioprosthetic valves.
Ghanbari H., Seifalian A. M., Viatge H., Tavakoli M., Burriesci G., Kidane A. G.   +5 more
core   +1 more source

Culture‐Negative Infective Endocarditis Presumed due to Brucella Causing Rapid Native Aortic Valve Destruction in a Young Adult: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Culture‐negative endocarditis with features consistent with Brucella can rapidly destroy a normal aortic valve in young adults. 2023 Duke‐ISCVID criteria (clinical/imaging findings plus histopathology), supported by serology and occupational exposure enabled urgent combined antimicrobial‐surgical management without culture confirmation ...
Baraa Nassar, Kristen I. Gharo, Olga Ramahi, Hussein Ghannam, Ahmed Romana, Kinda Abu Hashhash   +5 more
wiley   +1 more source