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Tissue-Engineered Heart Valve Prostheses: ‘State of the Heart‘
Regenerative Medicine, 2008In this article, we will review the current state of the art in heart valve tissue engineering. We provide an overview of mechanical and biological replacement options, outlining advantages and limitations of each option. Tissue engineering, as a field, is introduced, and specific aspects of valve tissue engineering are discussed (e.g., biomaterials ...
Francesco Migneco +2 more
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Pitfalls in statistical analysis of heart valve prostheses
The Annals of Thoracic Surgery, 1989Beware of the dangers of automated analysis, especially in multiple regression, and of overinterpretation of data. Do not let yourself be manipulated by numbers.
Albert Starr, Gary L. Grunkemeier
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Pulsatile flow experiments on heart valve prostheses
Medical & Biological Engineering & Computing, 1983In vitro fluid dynamic characteristics of aortic valve prostheses were experimentally measured for physiological relevant pulsatile flows using hot-film velocimetry. The prostheses studied were (i) centrally occluding ball-in-cage and (ii) tilting disc valves. The valves sewn to a plexiglass ring were placed in a specially designed valve chamber.
Herman L. Falsetti +3 more
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MECHANISMS OF HEMOLYSIS IN PATIENTS WITH HEART VALVE PROSTHESES
Acta Medica Scandinavica, 1971Abstract. Intravascular hemolysis was studied in a large, non‐selected series of patients with aortic and mitral valvular disease or valve prostheses in order to clarify the mechanisms of the erythrocyte destruction. Hemolysis was slight in unoperated patients, even in cases with severe valvular disease.
Jon Dale, Knut Rasmussen, Erik Myhre
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2010
Prosthetic heart valves may be mechanical or bioprosthetic. Mechanical valves, which are composed primarily of metal or carbon alloys, are classified according to their design as ball-caged, single-tilting-disc, or bileaflet-tilting-disc valves (Fig. 9.1). In ball-caged valves, the occluder is a sphere that is contained by a metal “cage” when the valve
Luigi P. Badano, Rosa Sicari
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Prosthetic heart valves may be mechanical or bioprosthetic. Mechanical valves, which are composed primarily of metal or carbon alloys, are classified according to their design as ball-caged, single-tilting-disc, or bileaflet-tilting-disc valves (Fig. 9.1). In ball-caged valves, the occluder is a sphere that is contained by a metal “cage” when the valve
Luigi P. Badano, Rosa Sicari
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Cavitation Dynamics of Mechanical Heart Valve Prostheses
Artificial Organs, 1994Abstract: Nine different mechanical mitral heart valves were chosen in order to study cavitation dynamics in detail in an in vitro flow system simulating a single event of mitral valve closure. The transvalvular pressure (ventricular minus atrial pressure) rise rate averaged during the valve closing period was used as an index of the loading rate.
Krishnan B. Chandran +2 more
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Cavitation Potential of Mechanical Heart Valve Prostheses
The International Journal of Artificial Organs, 1991Just like technical check valves, the function of mechanical heart valve prostheses may presumably also lead to cavitation effects during valve closure. Due to the waterhammer effect, cavitation may primarily occur in the mitral position leading to high mechanical loading of the valve itself and of corpuscular blood elements.
T. Graf, H. Fischer, G. Rau, H. Reul
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A hydraulic figure‐of‐merit for heart valve prostheses
Journal of Biomedical Materials Research, 1967AbstractThe pressure losses in the currently available prostheses are too high. We believe an excellent way to focus designers' attention upon this fact is to rank the various designs according to their hydraulic efficiency. The proposal of this paper is for pressure drop vs.
Lester R. Sauvage +2 more
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Antithrombotic Therapy in Patients With Heart Valve Prostheses
Cardiology in Review, 2013Heart valve prostheses carry a risk for thrombosis and require an antithrombotic strategy to prevent stroke, systemic embolism, and prosthetic valve thrombosis. Contemporary randomized trials to guide the clinician on the optimal anticoagulant treatment are scarce, and the validity of the historical data for current recommendations can be questioned in
Frans Van de Werf +6 more
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Design of a system for the accelerated loading of heart valve prostheses
Journal of Biomechanics, 1984In this paper an equipment is described for the loading of heart valve prostheses under physiological pressure conditions at a frequency of 10 Hz. The system consists essentially of two reservoirs between which a housing is mounted for holding the valve prosthesis. The reservoirs are partly filled with liquid.
van Aa Anton Steenhoven +3 more
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