Results 301 to 310 of about 2,331,622 (397)

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

British Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi, Dean Hickman, Ulrika S. H. Simonsson   +6 more
wiley   +1 more source

Toward developing a compact total artificial heart using a soft robotic fluidic transmission system. [PDF]

Sci Adv
Arfaee M, van Laake LC, Zou S, Bording C, Kluin J, Overvelde JTB.   +5 more
europepmc   +1 more source

IN VITRO MULTI-SCALE PATIENT-SPECIFIC MODELING OF HEMODYNAMICS IN STAGE 1 NORWOOD PALLIATION FOR THE TREATMENT OF SINGLE VENTRICLE HEART DISEASE

, 2015
Tianqi Hang
openalex   +1 more source

Virtual healthcare compared to hospital care for acute and post‐acute illness in adults: A systematic review and meta‐analysis of randomized controlled trials

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the clinical effectiveness, cost‐effectiveness, quality of life (QoL) and patient/caregiver satisfaction associated with VWs/HaH vs. traditional inpatient care in adults with acute or post‐acute illness. Methods We conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs), following PRISMA 2020 guidelines ...
Rana A. Malhis, Stuart E. Bond, Ahmed A. Sadeq, Rani Shatnawi, Barbara R. Conway, Syed Shahzad Hasan, Mamoon A. Aldeyab   +6 more
wiley   +1 more source

Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension. [PDF]

J Transl Med
Lo Muzio FP, Caputo A, Statello R, Hu M, Maestri R, Pelà G, Cabassi A, Burattini M, Rozzi G, Berrettoni S, Montanini B, Rossi S, Fassina L, Luciani GB, Condorelli G, Miragoli M.   +15 more
europepmc   +1 more source

Cardiomyopathies: Temporal Review and Genetic Determination. [PDF]

Biomedicines
Thiene G, Rizzo S, Basso C.
europepmc   +1 more source

The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

Hisler V, Rees L, Blanchoud S, Lischer HE, Bruggmann R, Jaźwińska A.   +5 more
europepmc   +1 more source

Prognostic Implication of Right Ventricular Hypertrophy in Patients With Hypertrophic Cardiomyopathy. [PDF]

Korean J Radiol
Hong SH, Park EA, Kwak SG, Kim HK, El-Naggar HM, Lee W.   +5 more
europepmc   +1 more source

Biopsy‐Proven Hydroxychloroquine‐Induced Cardiomyopathy in an Adolescent With Systemic Lupus Erythematosus

Arthritis &Rheumatology, Accepted Article.
Greta Mastrangelo, Anita Nagy, Aamir Jeewa, Deborah M Levy   +3 more
wiley   +1 more source

Sex-Specific Expression Patterns of <i>MYH6</i> and <i>MYH7</i> Gene Transcripts in Large Cohorts of Non-Failing and Failing Human Left Ventricular Tissues. [PDF]

J Cardiovasc Dev Dis
Červenák Z, Somorčík J, Jalali Y, Zajacová Ž, Baldovič M, Gažová A, Kyselovič J.   +6 more
europepmc   +1 more source