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The significance of heartburn [PDF]
QJM, 2000 Heartburn is a common symptom which 10% of the general population experience on a weekly basis.1,,2 Along with other symptoms of dyspepsia, it accounts for 1 in 20 GP consultations, with prescriptions for proton‐pump inhibitors consuming more than 6% of the primary‐care drugs budget.3,,4 Recent studies into the long‐term effects of reflux symptoms have
Brian T. Johnston
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Heartburn and effective herbal remedies: A systematic review study in Iranian ethnobotanical documents [PDF]
Journal of HerbMed Pharmacology, 2021 Every year, millions of people worldwide get sick with gastrointestinal diseases such as heartburn. Certain herbs contribute to the alleviation of heartburn, nausea, and improvement of digestion.
Gholam Basati +2 more
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Exploratory analyses of meal‐induced heartburn identify distinct clinical phenotypes of gastroesophageal reflux disease [PDF]
Physiological ReportsSymptoms in symptomatic GERD patients result from esophageal acid exposure and are treated with agents that inhibit gastric acid secretion. We analyzed data from a clinical trial evaluating the effect of ranitidine plus antacid on heartburn severity in ...
Jerry D. Gardner +1 more
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Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn
New England Journal of Medicine, 2019 BACKGROUND Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a frequent clinical problem with multiple potential causes. Treatments for PPI-refractory heartburn are of unproven efficacy and focus on controlling gastroesophageal ...
Stuart Jon Spechler +2 more
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Hiatus hernia and heartburn [PDF]
Gut, 1969 The symptoms in a group of 80 patients with a pure sliding hiatus hernia were investigated using the pyloric regulation test (Capper, Airth, and Kilby, 1966). It was found that there was a high correlation between the symptoms of heartburn and the reflux of duodenal barium into the stomach.
E W Gillison +4 more
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Diagnosis and Management of Gastroesophageal Reflux Disease: Current Insights [PDF]
Clinical and Experimental GastroenterologyAbhinav Vayal-Veettil,1,* C Prakash Gyawali2,* 1Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA; 2Division of Gastroenterology, Washington University School of Medicine, St.
Vayal-Veettil A, Gyawali CP
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Inconsistency in the Diagnosis of Functional Heartburn: Usefulness of Prolonged Wireless pH Monitoring in Patients With Proton Pump Inhibitor Refractory Gastroesophageal Reflux Disease [PDF]
Journal of Neurogastroenterology and Motility, 2015 Background/Aims The diagnosis of functional heartburn is important for management, however it stands on fragile pH monitoring variables, ie, acid exposure time varies from day to day and symptoms are often few or absent.
Domingues, G +5 more
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Alimentary Pharmacology and Therapeutics, 2019 Proton pump inhibitors (PPIs) are widely used to treat gastro‐oesophageal reflux disease (GORD). However, the onset of action is considered slow and PPIs cannot completely block acid secretion at night.
Tadayuki Oshima +2 more
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BMC Research Notes, 2020 Objective To determine if fermented soy supplementation relieves heartburn and improves gastrointestinal symptoms and quality of life, a randomized, double-blind parallel study was conducted with adults experiencing mild or moderate heartburn ...
Asmaa Fatani +4 more
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Patients Presenting With Reflux Symptoms - Whom to Test and Whom to Treat? [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal ResearchGastroesophageal reflux disease (GERD) is a complex condition with diverse clinical presentations, ranging from typical heartburn and regurgitation symptoms to extraesophageal manifestations and alarm symptoms. Determining which patients should be tested
Noy Lapidot Alon +2 more
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