Results 131 to 140 of about 59,312 (337)
Esophageal Epithelial-Derived IL-33 Is Upregulated in Patients with Heartburn
Background Interleukin-33 (IL-33) is a tissue-derived cytokine that is constitutively expressed in epithelial cells of tissues exposed to the environment and plays a role in sensing damage caused by inflammatory diseases. IL-33 acts as both a traditional
Hiroo Sei+10 more
semanticscholar +1 more source
Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome
ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod+68 more
wiley +1 more source
Pathophysiology of functional heartburn based on Rome III criteria in Japanese patients.
AIM To investigate the pathophysiology of functional heartburn (FH) in Japanese patients. METHODS A total of 111 patients with proton pump inhibitor (PPI)-refractory non-erosive gastroesophageal reflux disease underwent intraesophageal pressure testing
Yasuhiro Tamura+9 more
semanticscholar +1 more source
Urogynecologic Symptoms Are Not Specific to Anatomic Region of Digestive Symptoms
Urogynecologic symptoms are common in patients with DGBIs, regardless of the affected area of the GI tract. We recommend screening for these symptoms in all patients with chronic GI symptoms. ABSTRACT Background/Aims Many patients with digestive symptoms describe underlying urinary or gynecologic symptoms, which may increase visceral sensitivity in the
Madison Simons+5 more
wiley +1 more source
Treating heartburn in pregnancy: comparison of acid and alkali mixtures. [PDF]
R. D. Atlay+3 more
openalex +1 more source
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech+4 more
wiley +1 more source