Results 41 to 50 of about 60,448 (331)

Treatment of Gastrointestinal Disorders—Plants and Potential Mechanisms of Action of Their Constituents

open access: yesMolecules, 2022
The worldwide prevalence of gastrointestinal diseases is about 40%, with standard pharmacotherapy being long-lasting and economically challenging. Of the dozens of diseases listed by the Rome IV Foundation criteria, for five of them (heartburn, dyspepsia,
Szilvia Czigle   +5 more
doaj   +1 more source

Gastroesophageal reflux disease: risk factors, current possibilities of diagnosis and treatment optimisation

open access: yesМедицинский совет, 2022
Gastroesophageal reflux disease (GERD) is one of the most common causes of health care seeking at the primary care level in many countries. At an epidemiological level, GERD has been shown to be associated with a number of risk factors: obesity, tobacco ...
I. V. Maev   +3 more
doaj   +1 more source

Diagnosis and outcome of oesophageal Crohn's disease [PDF]

open access: yes, 2019
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D   +11 more
core   +1 more source

Randomised clinical trial: vonoprazan versus lansoprazole for the initial relief of heartburn in patients with erosive oesophagitis

open access: yesAlimentary Pharmacology and Therapeutics, 2019
Proton pump inhibitors (PPIs) are widely used to treat gastro‐oesophageal reflux disease (GORD). However, the onset of action is considered slow and PPIs cannot completely block acid secretion at night.
T. Oshima   +7 more
semanticscholar   +1 more source

Sustained efficacy following resolution of frequent heartburn with an over-the-counter regimen of esomeprazole 20 mg or placebo for 14 days: two randomized trials

open access: yesBMC Gastroenterology, 2018
Background A two-week course of therapy with an over-the-counter proton-pump inhibitor (PPI) is recommended for frequent heartburn. Limited research has been conducted on the sustained efficacy of short-term PPI therapy after treatment cessation ...
David A. Peura   +3 more
doaj   +1 more source

Ocular Side Effects of Sildenafil That Persist Beyond 24 h—A Case Series

open access: yesFrontiers in Neurology, 2020
Acute secondary effects of sildenafil, a first-line pharmacotherapy for erectile dysfunction (ED), include headache, heartburn, skin flush, and vision changes. Generally, these effects subside within 5 h.
Cüneyt Karaarslan
doaj   +1 more source

Anxiety Associated With Increased Risk for Emergency Department Recidivism in Patients With Low-Risk Chest Pain [PDF]

open access: yes, 2018
Anxiety contributes to the chest pain symptom complex in 30% to 40% of patients with low-risk chest pain seen in the emergency department (ED). The validated Hospital Anxiety Depression Scale-Anxiety subscale (HADS-A) has been used as an anxiety ...
Fry, Colin   +5 more
core   +1 more source

Comparison of symptoms, healthcare utilization, and treatment in diagnosed and undiagnosed individuals with diarrhea-predominant irritable bowel syndrome [PDF]

open access: yes, 2017
OBJECTIVES: Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by symptoms including abdominal pain and altered bowel function. Up to 75% of individuals with IBS may be undiagnosed.
Chang, Lin, Sayuk, Gregory S, Wolf, Ray
core   +2 more sources

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]

open access: yes, 2013
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Arnold, Dirk   +12 more
core   +1 more source

Health-related quality of life improves with treatment-related GERD symptom resolution after adjusting for baseline severity

open access: yesHealth and Quality of Life Outcomes, 2003
Severity and frequency of gastroesophageal reflux disease (GERD) related symptoms are associated with impaired health-related quality of life (HRQL). This study evaluated the association between baseline heartburn severity and endpoint HRQL of patients ...
Joshua-Gotlib Sandra   +4 more
doaj   +1 more source

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