Results 41 to 50 of about 60,448 (331)
The worldwide prevalence of gastrointestinal diseases is about 40%, with standard pharmacotherapy being long-lasting and economically challenging. Of the dozens of diseases listed by the Rome IV Foundation criteria, for five of them (heartburn, dyspepsia,
Szilvia Czigle +5 more
doaj +1 more source
Gastroesophageal reflux disease (GERD) is one of the most common causes of health care seeking at the primary care level in many countries. At an epidemiological level, GERD has been shown to be associated with a number of risk factors: obesity, tobacco ...
I. V. Maev +3 more
doaj +1 more source
Diagnosis and outcome of oesophageal Crohn's disease [PDF]
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D +11 more
core +1 more source
Proton pump inhibitors (PPIs) are widely used to treat gastro‐oesophageal reflux disease (GORD). However, the onset of action is considered slow and PPIs cannot completely block acid secretion at night.
T. Oshima +7 more
semanticscholar +1 more source
Background A two-week course of therapy with an over-the-counter proton-pump inhibitor (PPI) is recommended for frequent heartburn. Limited research has been conducted on the sustained efficacy of short-term PPI therapy after treatment cessation ...
David A. Peura +3 more
doaj +1 more source
Ocular Side Effects of Sildenafil That Persist Beyond 24 h—A Case Series
Acute secondary effects of sildenafil, a first-line pharmacotherapy for erectile dysfunction (ED), include headache, heartburn, skin flush, and vision changes. Generally, these effects subside within 5 h.
Cüneyt Karaarslan
doaj +1 more source
Anxiety Associated With Increased Risk for Emergency Department Recidivism in Patients With Low-Risk Chest Pain [PDF]
Anxiety contributes to the chest pain symptom complex in 30% to 40% of patients with low-risk chest pain seen in the emergency department (ED). The validated Hospital Anxiety Depression Scale-Anxiety subscale (HADS-A) has been used as an anxiety ...
Fry, Colin +5 more
core +1 more source
Comparison of symptoms, healthcare utilization, and treatment in diagnosed and undiagnosed individuals with diarrhea-predominant irritable bowel syndrome [PDF]
OBJECTIVES: Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by symptoms including abdominal pain and altered bowel function. Up to 75% of individuals with IBS may be undiagnosed.
Chang, Lin, Sayuk, Gregory S, Wolf, Ray
core +2 more sources
Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Arnold, Dirk +12 more
core +1 more source
Severity and frequency of gastroesophageal reflux disease (GERD) related symptoms are associated with impaired health-related quality of life (HRQL). This study evaluated the association between baseline heartburn severity and endpoint HRQL of patients ...
Joshua-Gotlib Sandra +4 more
doaj +1 more source

