Results 31 to 40 of about 270,077 (320)

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Critical Assessment of the Electric Effect in Electric Arc Welding

Metals, 2021
This work provides a critical assessment of electric effects on the microstructure evolution at the heat-affected zone in electric arc welding. Electric effects are the interactions between electromagnetic fields and materials’ microstructures.
Rongshan Qin
doaj   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Magnetic confinement of the solar tachocline: II. Coupling to a convection zone [PDF]

, 2011
The reason for the observed thinness of the solar tachocline is still not well understood. One of the explanations that have been proposed is that a primordial magnetic field renders the rotation uniform in the radiation zone. We test here the validity of this magnetic scenario through 3D numerical MHD simulations that encompass both the radiation zone
arxiv   +1 more source

FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier, Giulia F. Del Gobbo, Layla Mackay, Erika Wall, Madeline Couse, Laura M. McDonell, Mireille Cloutier, Matt C. Danzi, Jodi Warman‐Chardon, Pierre R. Bourque, Oksana Suchowersky, Alan Mears, Luke Seldenthuis, Wendy Mears, Laura Larrigan, Alexandre White‐Brown, Gerald Pfeffer, Dennis E. Bulman, David Dyment, Care4Rare Canada Consortium, Kym M. Boycott   +20 more
wiley   +1 more source

Overlapping Features and Microstructures of Coarse Grain Heat-Affected Zones in Swing Arc Narrow Gap GMA Welded EH40 Grade Steels

Crystals, 2022
Swing arc narrow gap GMA welding experiments were carried out with a Box–Behnken response surface design. Weld metal and heat-affected sizes were measured from the joints obtained, and an ANOVA was performed to obtain well-fitting models for definition ...
Zhida Ni, Fengya Hu, Bolun Dong, Xiaoyu Cai, Sanbao Lin   +4 more
doaj   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Pengaruh variasi kuat arus dan kecepatan pengelasan terhadap sifat mekanik hasil pengelasan SAW plat baja SS41 grade A

Jurnal Energi Dan Manufaktur, 2012
Welding is a method used to joint metal or metal alloy that take heat energy from welding machine. On welding process, there is occurred the fusion between base metal with filled metal.
IN Budiarsa, IGN Nitya Santhiarsa
doaj  

Temperature Field of FeCrNiCu Alloy Forming Layers of Continuous Wave/Pulsed Laser Remanufacture

Cailiao gongcheng, 2017
The temperature field of FeCrNiCu alloy forming layers of continuous wave(CW) and pulsed laser remanufacture was analyzed using the non-contact infrared thermometer.The general rule of temperature field distribution of molten pool and heat-affected zone ...
REN Wei-bin, DONG Shi-yun, XU Bin-shi, REN Jun-hua, ZHENG Xian-zhu, TONG Ji-feng   +5 more
doaj   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source