Spermidine-Regulated Biosynthesis of Heat-Stable Antifungal Factor (HSAF) in Lysobacter enzymogenes OH11 [PDF]
Heat-Stable Antifungal Factor (HSAF) and its analogs are antifungal natural products produced by the biocontrol agent Lysobacter enzymogenes. The production of HSAF is greatly influenced by environmental stimuli and nutrients, but the underlying ...
Yuan Chen +5 more
doaj +6 more sources
An Antifungal Polycyclic Tetramate Macrolactam, Heat-Stable Antifungal Factor (HSAF), Is a Novel Oxidative Stress Modulator in Lysobacter enzymogenes [PDF]
PoTeMs are a family of structurally distinct metabolites that have been found in a large number of bacteria. Although PoTeMs exhibit diverse therapeutic properties, the physiological function of PoTeMs in the producer microorganisms had not been investigated.
Lingjun Yu +4 more
openaire +3 more sources
Discovery of the microtubule‐severing protein as the target of antifungal compound heat‐stable antifungal factor in Fusarium graminearum and rational design of novel inhibitors [PDF]
Abstract BACKGROUND The natural compound heat‐stable antifungal factor (HSAF), produced by Lysobacter enzymogenes OH11, exhibits potent inhibitory activity against Fusarium graminearum
Jiamei Li +7 more
openaire +2 more sources
Hijacking competitor-derived signals: RcsB/C drives Lysobacter enzymogenes to exploit farnesol for enhanced antifungal capacity [PDF]
Microbial antagonism is a fundamental ecological process that shapes community composition and maintains ecosystem balance. However, the molecular signals, such as cross-kingdom interactions between bacteria and fungi in natural environments, remain ...
Fang Nan +7 more
doaj +2 more sources
Flow patterns and heat transfer for flow boiling in small to micro diameter tubes [PDF]
An overview of the recent developments in the study of flow patterns and boiling heat transfer in small to micro diameter tubes is presented. The latest results of a long-term study of flow boiling of R134a in five vertical stainless steel tubes of ...
Karayiannis, TG +3 more
core +6 more sources
Control of Wheat Fusarium Head Blight by Heat-Stable Antifungal Factor (HSAF) from Lysobacter enzymogenes [PDF]
Heat-stable antifungal factor (HSAF), which belongs to the polycyclic tetramate macrolactam family, was isolated from Lysobacter enzymogenes fermentations and exhibited inhibitory activities against a wide range of fungal pathogens. In this study, the antifungal activity of HSAF against Fusarium graminearum in vitro and in vivo was investigated.
Yangyang Zhao +7 more
openaire +2 more sources
Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Sonashia Velho-Pereira +1 more
core +1 more source
Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans [PDF]
Hsp12p is considered to be a small heat shock protein and conserved among fungal species. To investigate the expression of this heat shock protein in the fungal pathogen Candida albicans we developed an anti-CaHsp12p antibody.
Mühlschlegel, Fritz A. +16 more
core +1 more source
Control of glucosylceramide production and morphogenesis by the Bar1 ceramide synthase in Fusarium graminearum. [PDF]
The contribution of plasma membrane proteins to the virulence of plant pathogenic fungi is poorly understood. Accordingly, the objective of this study was to characterize the acyl-CoA dependent ceramide synthase Bar1 (previously implicated in plasma ...
William R Rittenour +3 more
doaj +1 more source
The biocontrol agent Lysobacter enzymogenes OH11 produces several structurally distinct antibiotic compounds, including the antifungal HSAF (Heat Stable Antifungal Factor) and alteramides, along with their 3-dehydroxyl precursors (3-deOH).
Lingjun Yu +3 more
doaj +1 more source

