Results 101 to 110 of about 5,291,187 (301)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Scalable brine treatment using 3D-printed multichannel thermodiffusion
npj Clean WaterIndustrial processes generate over 200 million metric tonnes of brine each day, posing serious environmental challenges due to its high salinity, toxicity, and energy-intensive treatment requirements.
Milad Mohsenzadeh +3 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Case Studies in Thermal EngineeringSteam generating heat pumps (SGHPs) offer a promising alternative to coal-fired boilers. To address the lack of general optimization strategy of autocascade SGHP (ASGHP) for variable operating conditions and variable cycle configurations, this paper ...
Xudong Ma +4 more
doaj +1 more source
Chemical and Process Engineering, 2015 The aim of the study was to examine the efficiency of the thermal wave type adsorption refrigerating equipment working on a pair of activated carbon and methanol. Adsorption units can work in trigeneration systems and in applications driven by waste heat.
Grzebielec Andrzej +2 more
doaj +1 more source
Tube shape selection for heat recovery from particle-laden exhaust gas streams [PDF]
, 2011 Heat recovery from exhaust gas streams is applicable to a wide variety of industries. Two problems encountered in exhaust gas heat recovery are: the high heat transfer resistance of gases and the presence of entrained particulate matter, which can limit ...
Atkins, Martin John +4 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
MATEC Web of Conferences, 2017 Problem of the automatic thermogradient stabilization of the constructive elements sizes is discussed. The actual problem is the determination of the control algorithm controlled heat sources, providing them with the minimum possible number of minimal ...
Livshits Michael Yu. +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source