Results 101 to 110 of about 5,363,306 (301)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 1978 A heat exchanger, as exemplified by a rocket combustion chamber, is constructed by stacking thin metal rings having microsized openings therein at selective locations to form cooling passages defined by an inner wall, an outer wall and fins.
Sokolowski, D. E.
core +1 more source
Cooling Performance of a Novel Circulatory Flow Concentric Multi-Channel Heat Sink with Nanofluids [PDF]
, 2020 Heat rejection from electronic devices such as processors necessitates a high heat removal rate. The present study focuses on liquid-cooled novel heat sink geometry made from four channels (width 4 mm and depth 3.5 mm) configured in a concentric shape ...
Ahmadi, Mohammad H. +4 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The environmental impact of refuse derived fuel co-combustion with lignite
MATEC Web of Conferences, 2018 Legal regulations on waste disposal require waste producers to limit landfilling and to find different ways of waste management, the preferred methods being recycling of material and energy potential.
Krawczyk Piotr +2 more
doaj +1 more source
, 1974 Heat flow calorimeter devices are used to measure heat liberated from or absorbed by an object. This device is capable of measuring the thermal output of sealed nickel-cadmium batteries or cells during charge-discharge cycles.
Fletcher, J. C., Johnston, W. V.
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
High thermal power density heat transfer apparatus providing electrical isolation at high temperature using heat pipes [PDF]
, 1985 This invention is directed to transferring heat from an extremely high temperature source to an electrically isolated lower temperature receiver. The invention is particularly concerned with supplying thermal power to a thermionic converter from a ...
Morris, J. F.
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Scalable brine treatment using 3D-printed multichannel thermodiffusion
npj Clean WaterIndustrial processes generate over 200 million metric tonnes of brine each day, posing serious environmental challenges due to its high salinity, toxicity, and energy-intensive treatment requirements.
Milad Mohsenzadeh +3 more
doaj +1 more source