Results 41 to 50 of about 224,355 (256)
Fluids, 2021 The constant growth of urban agglomerations with the development of transport networks requires the optimal use of energy and new ways of storing it. Energy efficiency is becoming one of the main challenges of modern engineering.
Nadezhda S. Bondareva +1 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Applied Sciences, 2020 Cylinder-shaped fuel pellets that were 3 mm in diameter and 3 mm in height, with a mass of 20 mg, were produced by compressing dry coal processing waste under the pressure of 5 MPa. The first group of pellets from coal dust with a particle size less than
Dmitriy Klepikov +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Investigation of the regularities of vortical flows in a cyclone-bed chamber
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2018 Experimental investigation of the radial distributions of tangential and longitudinal velocities, total and static pressures in the vortex zone of a cyclone-bed chamber of diameter 0.21 m has been carried out.
E. A. Pitsukha +2 more
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Isothermal Evaporation Rate of Deposited Liquid Aerosols and the SARS-CoV-2 Coronavirus Survival
Aerosol and Air Quality Research, 2020 It is shown that the evaporation rate of a liquid sample with the height is about several millimeters containing the culture of coronavirus affects its survival on a substrate.
Pavel S. Grinchuk +3 more
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Applied Sciences, 2020 The present study deals with the experimental research findings for the characteristics of ignition (ignition delay times, minimum ignition temperature) and combustion (maximum combustion temperature, concentration of anthropogenic emission), as well as ...
Dmitrii Glushkov +3 more
doaj +1 more source