Results 41 to 50 of about 214,011 (256)
Applied Sciences, 2020 Cylinder-shaped fuel pellets that were 3 mm in diameter and 3 mm in height, with a mass of 20 mg, were produced by compressing dry coal processing waste under the pressure of 5 MPa. The first group of pellets from coal dust with a particle size less than
Dmitriy Klepikov +3 more
doaj +1 more source
Fluids, 2021 The constant growth of urban agglomerations with the development of transport networks requires the optimal use of energy and new ways of storing it. Energy efficiency is becoming one of the main challenges of modern engineering.
Nadezhda S. Bondareva +1 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Investigation of the regularities of vortical flows in a cyclone-bed chamber
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2018 Experimental investigation of the radial distributions of tangential and longitudinal velocities, total and static pressures in the vortex zone of a cyclone-bed chamber of diameter 0.21 m has been carried out.
E. A. Pitsukha +2 more
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Applied Sciences, 2020 The present study deals with the experimental research findings for the characteristics of ignition (ignition delay times, minimum ignition temperature) and combustion (maximum combustion temperature, concentration of anthropogenic emission), as well as ...
Dmitrii Glushkov +3 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
MATEC Web of Conferences, 2017 The results of the mathematical simulation of the coal-water fuel particle in the conditions of electric-spark discharge have been given.
Syrodoy Samen +3 more
doaj +1 more source