Results 101 to 110 of about 262,009 (305)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

NEW MECHANISMS FOR NANOINDENTATION DATA PROCESSING USING ATOMIC FORCE MICROSCOPY METHOD

open access: yesНаука и техника, 2015
Elastic modulus accuracy using atomic force microscopy  depends significantly on processing quality of the experimental data obtained during nanoindentation.  Multiply repeated calibration can lead to conservative value of the calibration factor.
A. A. Mohammed Salem   +3 more
doaj  

Experimental study on heat and mass transfer for heating milk

open access: yesJournal of Energy in Southern Africa, 2011
In this paper, an attempt has been made to estimate the convective heat transfer coefficient for sensible heating of milk in a stainless steel pot during khoa, made by traditional method. Various indoor experiments were performed for simulation of a developed thermal model for maximum evaporation by varying heat inputs from 240 watts to 420 watts.
Kumar, Mahesh   +3 more
openaire   +3 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Heat and Mass Transfer [PDF]

open access: yesJournal of Applied Mechanics, 1960
E. R. G. Eckert   +2 more
openaire   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Investigation of heat transfer in metal-foam tubes [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Nowadays metallic foams attract increasing attention in making compact heat exchangers due to its advanced thermal properties.
Lu, Wei
core  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

COMPARISON OF THE RESULTS OF CALCULATION OF THE STEEL SLUGS HEATING IN FURNACE WITH PACING BACKSTONE WITH THE EXPERIMENTAL DATA

open access: yesЛитьë и металлургия, 2006
The comparison of the results of the temperature regimes of the heating furnace with pacing backstone with experimental data, received in terms of operating production at working of furnace with varied capacity is carried out.
V. I. Timoshpolskij   +4 more
doaj  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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