Results 81 to 90 of about 80,903 (204)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Investigation of heat transfer in metal-foam tubes [PDF]
, 2008 The flow boiling heat transfer performance in horizontal metal-foam tubes is numerically investigated based on the flow pattern map retrieved from experimental investigations. The flow pattern and velocity profile are generally governed by vapour quality
Zhao, Changying +3 more
core +2 more sources
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Mass or heat transfer inside a spherical gas bubble at low to moderate Reynolds number [PDF]
, 2013 Mass (or heat) transfer inside a spherical gas bubble rising through a stationary liquid is investigated by direct numerical simulation. Simulations were carried out for bubble Reynolds number ranging from 0.1 to 100 and for Péclet numbers ranging from 1
Colombet, Damien +3 more
core +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
WORKING PROCESS OF INTERNAL COMBUSTION ENGINE RUNNING ON ENRICHED HYDROGEN GASOLINE-AIR MIXTURE
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2018 The effect of hydrogen additives on the working process of a piston-type gasoline engine is studied. The indicator diagram has been built, and the operation of the piston engine on gasoline-air mixtures enriched with hydrogen in the amount of 0…20 % of ...
M. S. Assad +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Литьë и металлургия, 2006 The forecast of formation of the ferrous metals chips in the Republic of Belarus is carried out.
V. I. Timoshpolski +3 more
doaj
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source