Results 61 to 70 of about 431,560 (339)

Modelling linered engine blocks [PDF]

open access: yes, 1991
Factors that affect heat transfer in the linered aluminium engine block are examined to determine their importance. Conduction is found to be the dominant mode of heat transfer, and the interface is characterised as imperfect contact if there are no ...
Ha, J.
core  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Natural Convection Heat Transfer from an Isothermal Plate

open access: yesThermo, 2023
Using boundary-layer theory, natural convection heat transfer formulas that are accurate over a wide range of Rayleigh numbers (Ra) were developed in the 1970s and 1980s for vertical and downward-facing plates.
Aubrey Jaffer
doaj   +1 more source

Start up system for hydrogen generator used with an internal combustion engine [PDF]

open access: yes, 1977
A hydrogen generator provides hydrogen rich product gases which are mixed with the fuel being supplied to an internal combustion engine for the purpose of enabling a very lean mixture of that fuel to be used, whereby nitrous oxides emitted by the engine ...
Cerini, D. J., Houseman, J.
core   +1 more source

Dissipative heat engine is thermodynamically inconsistent

open access: yes, 2009
A heat engine operating on the basis of the Carnot cycle is considered, where the mechanical work performed is dissipated within the engine at the temperature of the warmer isotherm and the resulting heat is added to the engine together with an external ...
Gorshkov, V. G., Makarieva, A. M.
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Verification of ignition energy time distribution control for a diluted combustion engine

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Several high energy ignitions have been proposed to improve ignition performance of diluted combustion recently. One of the major issues in the high energy ignition systems is heat generation of an ignition coil due to increase of power consumption. This
Eiichiro OHATA, Kazuhiro ORYOJI
doaj   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

The Thermodynamics of Heat Engines [PDF]

open access: yesNature, 1903
THIS is a very good specimen of that sort of book which is an amplification of the lecture notes of a professor who has carefully prepared problems for students. We may not always like the way in which he introduces the subject to his pupils, and we may say that it is unphilosophical and even cryptic, and sometimes too brilliant, but such comments are ...
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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