Results 181 to 190 of about 32,759 (250)

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

BMEMat, EarlyView.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan, Yuchan Xue, Miao Zhang, Zihao Zhang, Shiyu Peng, Minghao Sui, Han Ding, Yingying Nie, Yuemin Feng, Le Wang, Tianru Zhang, Mingchuan Yu, He Xia, Hong Liu, Qiang Zhu, Songbo Zhao   +15 more
wiley   +1 more source

Reversing T cell dysfunction in a novel <i>in vitro</i> model of T cell exhaustion reveals differential roles of RASA2. [PDF]

Front Immunol
Saraç H, Nicholson R, Graham RN, Augustus M, Taghavi R, Connolly DJ, Lim L, Lourenco S.   +7 more
europepmc   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

CARD9-dependent macrophage plasticity regulates effective fungal clearance. [PDF]

J Clin Invest
Zhang L, Tang Z, Zhang Y, Liu W, Jiang H, Yu L, Lei K, Ma Y, Fu YX, Li R, Wang W, Bai F, Wang X.   +12 more
europepmc   +1 more source

Upregulation of the TCA Cycle and Oxidative Phosphorylation Enhances the Fitness of CD99 CAR-T Cells Under Dynamic Cultivation. [PDF]

Int J Mol Sci
Zhao J, Wang Y, Wang Y, Dong G, Wu H, Cui Y, Gu L, Zhao F, Zhao G, Kang J, Zhang Q, Liu N, Wang N, Sun X, Xu Y, Zhang T, Shi J.   +16 more
europepmc   +1 more source

Can Body Mass Index Values and/or Player Position be Viable Predictors for Exertional Heat Illness in American Football Players? [PDF]

Sports Health
Cahill OJ, Cooper ER, Grundstein AJ.
europepmc   +1 more source

International migrant workers, heat exposure, and climate change: a systematic review of health risks and protective interventions. [PDF]

BMC Glob Public Health
Van der Horst L, Bouaddi O, Williams S, Jago M, Lau K, Furber B, Zaini AZ, El-Ghitany EM, Loganathan T, Flouris AD, Testa DJ, Zimmerman C, Hargreaves S, Consortium for Migrant Worker Health.   +13 more
europepmc   +1 more source

Contrasting functions of CD73 and adenosine in CD8+ T-cell exhaustion during antitumor immunity. [PDF]

Oncoimmunology
Saavedra-Almarza J, Gouët S, Malgue F, Bascuñan C, Hernández-Oliveras A, De la Rosa J, Reyes-Alvarez J, Villaman C, Corrales-Bermúdez J, Castañeda J, García-Gómez M, Martin AJM, Lladser Á, Rosemblatt M, Bono MR, Sauma D.   +15 more
europepmc   +1 more source