Results 191 to 200 of about 122,925 (317)
Critical determinants of morbidity and adverse outcomes during the Hajj using the Haddon matrix and the combined model. [PDF]
Almuzaini Y +3 more
europepmc +1 more source
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu +14 more
wiley +1 more source
The Effect of Three Precooling Methods on Endurance Performance in Active Men. [PDF]
Mirzae B +3 more
europepmc +1 more source
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Acute Effects of Caffeine and Taurine Co-Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat. [PDF]
Aggett J +8 more
europepmc +1 more source
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia +11 more
wiley +1 more source
Improving Energy and Environmental Efficiency of Co-processing of Coal and Biomass Processes [PDF]
Lugova, Yulia +2 more
core
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Postural stability and neurobehavioural effects of heat exhaustion among adult men
Sin Eng Chia, Kwang-Joo Teo
openalex +2 more sources

