Results 121 to 130 of about 4,691,836 (302)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Additive layer manufactured sinter-style aluminium/ammonia heat pipes [PDF]

open access: yes, 2012
A novel heat pipe (HP) manufacturing method has been developed based on an additive layer manufacturing technique called “selective laser melting” or SLM.
Masoud Ameli, Seied
core  

Cool It! On Energy Dissipation, Heat Generation and Thermal Degradation: The Microstructurothermal Entropy and Its Application to Real-World Systems

open access: yesApplied Mechanics
Thermodynamic free energy is used to elucidate the significance of energy dissipation-induced temperature rise on the performance, reliability, and durability of all systems, biological, chemical and physical.
Jude A. Osara
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The influence of return bends on the downstream pressure drop and condensation heat transfer in tubes [PDF]

open access: yes, 1971
The influence of return bends on the downstream pressure drop and heat transfer coefficient of condensing refrigerant R-12 was studied experimentally. Flow patterns in glass return bends of 1/2 to 1 in. radius and 0.315 in. I. D.
Traviss, Donald P., Rohsenow, Warren M.
core  

Suitability of Embedded Liquid Cooling and Heat Generation for Chips. [PDF]

open access: yesMicromachines (Basel), 2023
Zhang J   +5 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Optimum geometry of solid porous spheres with heat generation [PDF]

open access: yes, 2012
Paper presented at the 9th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Malta, 16-18 July, 2012.Spent nuclear fuel has to be cooled so that the decay heat generated does not melt the containment system, which could lead ...

core  

HEAT GENERATION AND RESISTANCE TO DEFORMATION OF STRUCTURAL STEEL

open access: yesНаука и техника, 2015
The purpose of this paper is to determine dependence between heat generation and resistance to deformation of structural steel.It has been assumed on the basis of the represented data that in the course of deformation of structural steel physicochemical ...
A. E. Moyseychik, Yu. V. Vasilevich
doaj  

Understanding Heat Generation of LNMO Cathodes in Lithium-Ion Batteries via Entropy and Resistance

open access: yesBatteries
The heat generation of lithium-ion batteries is a critical parameter, as it significantly affects cell temperature. Poor thermal management can lead to elevated cell temperatures, accelerating side reactions, reducing cell lifetime, and, in extreme cases,
Kevin Böhm   +3 more
doaj   +1 more source

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