Results 41 to 50 of about 334,185 (255)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dynamic Model for the EV’s Charging Infrastructure Planning Through Finite Element Method

open access: yesIEEE Access, 2020
The rapid increase in the number of electric vehicles around the world, the high demands on the charging stations, and the challenges for locating the charging stations made researchers around the globe to think for a proper solution.
Morris Brenna   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Regional maps of occupational heat exposure: past, present, and potential future

open access: yesGlobal Health Action, 2010
Background: An important feature of climate change is increasing human heat exposure in workplaces without cooling systems in tropical and subtropical countries.
Tord Kjellstrom   +2 more
doaj   +1 more source

Mapping Heat in the U.S. Financial System [PDF]

open access: yesSSRN Electronic Journal, 2015
We provide a framework for assessing the build-up of vulnerabilities to the U.S. financial system. We collect forty-four indicators of financial and balance-sheet conditions, cutting across measures of valuation pressures, nonfinancial borrowing, and financial sector health.
David Aikman   +4 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparative Study of Cognitive Differences in Rural Landscapes Based on Eye Movement Experiments

open access: yesLand
With the booming development of rural tourism, the users of rural environments are gradually becoming more diverse. Both tourists and villagers are the main appreciators of rural landscapes, but the cognitive similarities and differences in rural ...
Yanbo Wang   +4 more
doaj   +1 more source

Evaluating different geothermal heat-flow maps as basal boundary conditions during spin-up of the Greenland ice sheet [PDF]

open access: yesThe Cryosphere
There is currently poor scientific agreement on whether the ice–bed interface is frozen or thawed beneath approximately one third of the Greenland ice sheet.
T. Zhang   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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