Results 91 to 100 of about 2,407,874 (313)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Water‐Efficient Smart Drip Irrigation Enabled by a Low‐Power and High‐Efficiency Flexible Electromagnetic Actuator

Advanced Science, EarlyView.
Water scarcity poses a critical threat to global food security. A low‐power, flexible electromagnetic actuator is presented for smart drip irrigation systems. The device achieves precise, wide‐range flow modulation (0.05–5.8 mL/min) in response to real‐time plant demands, reducing water consumption compared to conventional flood irrigation.
Duo Chen, Xubin Zhu, Minwei Zhang, Kerui Li, Qinghong Zhang, Yaogang Li, Chengyi Hou, Hongzhi Wang   +7 more
wiley   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Heat Transfer Performance of a 3D-Printed Aluminum Flat-Plate Oscillating Heat Pipe Finned Radiator. [PDF]

Nanomaterials (Basel), 2023
Xiao X, He Y, Wang Q, Yang Y, Chang C, Ji Y.   +5 more
europepmc   +1 more source

From Complex Shaping to Mirror Finish: Additive Manufacturing of Aerospace‐grade Cf/SiC Space Optics

Advanced Science, EarlyView.
An integrated additive manufacturing route combines selective laser sintering, engineered interphases, and optimized silicon infiltration to fabricate complex Cf/SiC composites. The approach enables precise shaping, high mechanical performance, and excellent optical reflectivity, offering a scalable solution for advanced aerospace optics with both ...
Buhao Zhang, Li Wang, Xiao Chen, Yuquan Wei, Huisheng Tian, Zhengren Huang, Xuejian Liu, Zhongming Chen, Jie Yin   +8 more
wiley   +1 more source

Transient Numerical Analysis of Single Heat Pipe Failure in Heat Pipe Reactor

Yuanzineng kexue jishu
As means to meet the needs of long-distance energy supply, safe power supply for remote areas facilities, power supply for the surface of the moon and Mars, and deep space and deep-sea exploration, the application of nuclear energy has attracted more and
HAN Ye1, , YANG Siyuan2, WEN Qinglong2, CHAI Baohua1, ZHANG Yakun1
doaj   +1 more source

Polymeric Materials Selection for Flexible Pulsating Heat Pipe Manufacturing Using a Comparative Hybrid MCDM Approach. [PDF]

Polymers (Basel), 2023
Ordu M, Der O.
europepmc   +1 more source

Unveiling the Formation and Evolution of the Cathode–Electrolyte Interphase in Lithium–Sulfur Batteries

Advanced Science, EarlyView.
By integrating electrochemical impedance spectroscopy (EIS), background‐subtracted in situ Fourier‐transform infrared (FTIR) spectroscopy, and X‐ray absorption spectroscopy (XAS), this work reveals electrolyte decomposition and the reduced species involved in forming the cathode–electrolyte interphase (CEI) in lithium–sulfur batteries (LSBs), offering ...
Murilo Machado Amaral, Otavio Jovino Marques, André de Navarro de Miranda, Aline Carlos Oliveira, Gustavo Doubek, Gurpreet Singh, Hudson Zanin, Renato Garcia Freitas, Johanna Nelson Weker, Pablo Sebastian Fernandez   +9 more
wiley   +1 more source

Analysis of Steady State Performance of High Temperature Flat Heat Pipe Under Non-uniform Heating

Yuanzineng kexue jishu, 2023
Heat pipe reactor has the advantages of miniaturization, high inherent safety, and simple structure, which has extensive application prospects and research significance in the fields of universe exploration and distributed power generation.
YU Lianyun;YANG Yi
doaj