Results 221 to 230 of about 2,407,874 (313)

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

open access: yesCytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

A perspective review of applications of the computed tomography (CT) scan imaging technique for microscopic reservoir rock characterization

open access: yesDeep Underground Science and Engineering, EarlyView.
In this review, the application of micro‐CT and medical‐CT scanning in the oil and gas industry has been thoroughly discussed. Recent improvements in DRP and modern imaging techniques in the oil and gas industry have been modeled using both experimental and simulation work.
Achinta Bera   +2 more
wiley   +1 more source

Experimental study on burning rate and flame geometry in construction tunnel fires under high geothermal conditions

open access: yesDeep Underground Science and Engineering, EarlyView.
Abstract As tunnel construction advances in lengths and depths, the construction of tunnels in high geothermal environments has become increasingly common, raising significant fire risks. In this study, a 1:20 scale model tunnel test platform was constructed to investigate the effects of a high geothermal environment on fire behavior in tunnels during ...
Xiaoxian Fei   +6 more
wiley   +1 more source

An assessment of stress and production rate of sucker rod heat pipes in oil well pumping system

open access: yesDeep Underground Science and Engineering, EarlyView.
The sucker rod pumping system is the preferred oil extraction technique. The concept about equipping the hollow vacuum space in solid sucker rods with heat pipe has been scrutinized in terms of stress and oil production evaluation. Abstract The implementation of the heat pipe concept in sucker rods for oil pumping systems negates the requirement for an
R. S. Anand   +5 more
wiley   +1 more source

Caving‐enhanced geothermal system overwhelms fracturing‐ and pipe‐enhanced geothermal system in heat extraction

open access: yesDeep Underground Science and Engineering, EarlyView.
Our study reveals that caving‐enhanced geothermal systems (C‐EGS) with adequately fractured reservoirs achieve optimal heat extraction by minimizing preferential flow paths, while conventional fracturing (F‐EGS) and pipe‐based (P‐EGS) systems suffer accelerated thermal drawdown.
Fangchao Kang   +4 more
wiley   +1 more source

Strengthening urban resilience in China through underground infrastructures management: Addressing global climate challenges with technological solutions

open access: yesDeep Underground Science and Engineering, EarlyView.
This paper explores how climate‐resilient technologies, such as smart grids, digital twins, and self‐healing materials, can enhance urban resilience. It highlights the urgent need for proactive planning, public‐private collaboration, and data‐driven innovation to future‐proof underground infrastructure amid accelerating climate and urban pressures ...
Kai Chen Goh   +12 more
wiley   +1 more source

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