Results 161 to 170 of about 345,579 (193)

Molecular detection and characterisation of fungal heat shock protein 60

Mycoses, 2011
SummaryHeat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up‐regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties.
Reinhard B, Raggam, Helmut J F, Salzer, Egon, Marth, Bettina, Heiling, Astrid H, Paulitsch, Walter, Buzina   +5 more
openaire   +2 more sources

Heat shock protein 60: regulatory role on innate immune cells

Cellular and Molecular Life Sciences, 2007
Human heat shock protein 60 (Hsp60) exhibits immunoregulatory properties, primarily by inducing pro-inflammatory responses in innate immune cells. Extensive analyses identified specific receptor structures for the interaction of Hsp60 with these cells.
C, Habich, V, Burkart
openaire   +2 more sources

Picornavirus proteins share antigenic determinants with heat shock proteins 60/65

Journal of Medical Virology, 2000
Immunological cross-reactions between enteroviruses and islet cell autoantigens have been suggested to play a role in the etiopathogenesis of insulin dependent diabetes mellitus (IDDM). In the nonobese diabetic mouse, an autoimmune model of IDDM, one of the reactive beta cell autoantigens is the heat shock protein 60 (HSP60).
T, Härkönen, M, Puolakkainen, M, Sarvas, U, Airaksinen, T, Hovi, M, Roivainen   +5 more
openaire   +2 more sources

Role of heat shock protein 60 (HSP60) on paraquat intoxication

Journal of Applied Toxicology, 2001
AbstractThe possibility of establishing a new method of treatment against pulmonary fibrosis caused by acute paraquat intoxication, which takes into consideration the role of heat shock protein 60 (HSP60), was investigated in paraquat‐exposed rat lung mitochondria.
A, Kaetsu, T, Fukushima, S, Inoue, H, Lim, M, Moriyama   +4 more
openaire   +2 more sources

Heat Shock Protein 60 and Type I Diabetes

1999
Type I diabetes is characterised by the destruction of pancreatic insulin secreting beta cells and is commonly believed to have an autoimmune aetiology. During the clinically silent, early stages of disease the pancreas is infiltrated by inflammatory cells which mediate beta cell damage.
S. G. Newton, D. M. Altmann
openaire   +1 more source

AB0604 Heat Shock Protein Gene-60 (HSP 60) Polymorphism in Behcet's Disease

Annals of the Rheumatic Diseases, 2014
Background Behcet9s Disease (BD) has the hallmarks of complex genetic disorder. The most established genetic marker-HLA B51 does not account for more than 20% of the relative risk in siblings of affected individuals. Heat shock proteins (HSP) might stimulate both innate and adaptive immune mechanisms in BD.
Z. Ozbalkan, I. Ertenli, S. Kiraz, M.A. Ozturk, M. Mısırlıoglu, S. Tuncer, Y. Karaaslan, M. Calguneri   +7 more
openaire   +1 more source

[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2006
To study the role of heat shock protein (HSP) 60 and HSP70 in the pathogenesis of oral lichen planus (OLP).The immunohistochemical SP methods were used to detected the expression of HSP60 and HSP70 in 62 cases of oral lichen planus, 10 cases of normal oral mucosa, 21 cases of chronic discoid lupus erythematosus (DLE), 10 cases of benign lymphoadenosis ...
Ping, Di, Yan, Gao
openaire   +1 more source

Analysis of heat shock protein 60 epitopes in transgenic mice

Biochemical Society Transactions, 1997
S G, Newton, D M, Altmann
openaire   +2 more sources

Heat shock factors: integrators of cell stress, development and lifespan

Nature Reviews Molecular Cell Biology, 2010
Richard I Morimoto, Lea Sistonen
exaly  

Regulation of heat shock transcription factors and their roles in physiology and disease

Nature Reviews Molecular Cell Biology, 2017
Rocio Gomez-Pastor, Dennis J Thiele
exaly