Small but crucial : the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans [PDF]
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A Dereeper +133 more
core +4 more sources
Diversification of the Caenorhabditis heat shock response by Helitron transposable elements. [PDF]
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Ahringer +84 more
core +2 more sources
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 [PDF]
Cancer therapeutics: Extending a drug's reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment.
Chae, Young Chan +10 more
core +1 more source
A freshwater Pomacea canaliculata snail is widely spread across countries, including Iraq, and has the possibility for habitat alterations and lives under unusual conditions.
Sarmad Awad Mozan AL-Asadi +4 more
doaj +1 more source
HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. [PDF]
Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress.
Chen, Xuemei +5 more
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Surviving the heat of the moment : a fungal pathogens perspective [PDF]
Peer reviewedPublisher ...
Cowen, Leah E, Leach, Michelle D
core +2 more sources
Background The thermotolerance of Aspergillus fumigatus plays a critical role in mammalian and avian infections. Thus, the identification of its adaptation mechanism to higher temperature is very important for an efficient anti-fungal drug development as
Miyano Satoru +2 more
doaj +1 more source
Relationships Among Beef Cow Productivity Traits and Single Nucleotide Polymorphisms in the Bovine Heat Shock Protein 70 Gene [PDF]
When eukaryotes are exposed to stressors such as heat, toxins, and low oxygen levels, heat shock proteins (HSPs) are synthesized to maintain normal cellular function within the body.
Finney, Ashley
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Hyperglycemia and antibody titres against heat shock protein 27 in traumatic brain injury patients on parenteral nutrition [PDF]
Objective(s):Hyperglycemia worsens the neuronal death induced by cerebral ischemia. Previous studies demonstrated that diabetic hyperglycemia suppressed the expression of heat shock protein 70 and 60 (HSP70 and 60) in the liver.
Seyedeh Neda Mousavi +6 more
doaj
Glutamate leads to neuronal cell damage by generating neurotoxicity during brain development. The objective of this study is to identify proteins that differently expressed by glutamate treatment in neonatal cerebral cortex. Sprague-Dawley rat pups (post-
Ju-Bin Kang, Dong-Ju Park, Phil-Ok Koh
doaj +1 more source

