Results 111 to 120 of about 222,334 (313)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Energies, 2019 The quality of internal air is one of the factors that affect the pace and quality of knowledge acquisition. Therefore, it is important that classrooms have high quality of air.
Katarzyna Gładyszewska-Fiedoruk +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ENERGY SAVING IN HEAT SUPPLY [PDF]
, 2021 The paper lists the main causes of energy losses in heating networks. The directions of energy saving in heat supply systems are considered, as well as the main ways of solving the problem associated with increasing the energy efficiency of heat supply ...
Velchinskaya, P. A. +3 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Indicators of reliability of heat supply organizations
, 2017 One of the key indicators of heat supply organizations is the reliability of energy facilities. The index of reliability of heat supply organization is of interest to potential investors, to assess the risks of investing projects.
I. G. Akhmetova
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Domestic Heat Pump System With Solar Thermal Collectors as Heat Source and Annual Ice Storage
, 2012 Aim of this paper is a theoretical and experimental investigation of a domestic heating system with heat pump using solar thermal collectors as the only heat source.
Gschwend, Andreas, Bertsch, Stefan S.
core +1 more source
Energy Efficiency Challenges in Heating Supply System of Turkmenistan and Potential Solutions [PDF]
, 2010 The poor condition and inefficient operation of the existing heat and hot water supply system in Turkmenistan is causing serious economic, social and environmental problems.
Behnke, R., Zomov, A.
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Seasonal concentration distribution of PM1.0 and PM2.5 and a risk assessment of bound trace metals in Harbin, China: Effect of the species distribution of heavy metals and heat supply. [PDF]
Sci Rep, 2020 Wang K +9 more
europepmc +1 more source