Results 31 to 40 of about 398,956 (258)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

UNCONTROLLED PHOTOMULTIPLIER CURRENT IN PHOTOEMISSION ANALYSIS

open access: yesПриборы и методы измерений, 2016
The dependence of photon energy from energy of photoelectron is base of photoemission radiation analysis. In such photoemission measurements except current of photocathode is always exist a reverse current from the collector of electrons to the ...
K. A. Viazava   +2 more
doaj   +1 more source

Key Areas of Gas Hydrates Study: Review

open access: yesEnergies, 2022
Gas hydrates are widespread all over the world. They feature high energy density and are a clean energy source of great potential. The paper considers experimental and theoretical studies on gas hydrates in the following key areas: formation and ...
Olga Gaidukova   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Preparation and characterization of an aluminum ammonium sulfate dodecahydrate-based composite phase change material with low supercooling and high thermal conductivity

open access: yesCase Studies in Thermal Engineering
Aluminum ammonium sulfate dodecahydrate (AASD) is a promising hydrated salt-type phase change material. However, its application is severely hindered by its large undercooling and low thermal conductivity.
Zhansheng Fan   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Experimental Study of the Vapor Temperature in the Reaction Zone for Producing Liquid from Camphor Wood in a Non-sweeping Gas Fixed-bed Pyrolysis Reactor

open access: yesInternational Journal of Technology, 2018
The liquids produced by the pyrolysis process with biomass as the raw material are popularly called bio-oil. The reaction zone temperature in the pyrolysis process affects the liquid yield in a non-sweeping gas fixed-bed reactor.
Nasruddin A Abdullah   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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