Results 81 to 90 of about 6,852,964 (392)

Modelling and simulation techniques for forced convection heat transfer in heat sinks with rectangular fins [PDF]

open access: yes, 2009
The official published version of this article can be found at the link below.This paper provides a comprehensive description of the thermal conditions within a heat sink with rectangular fins under conditions of cooling by laminar forced convection. The
Aung   +14 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

R134a flow boiling heat transfer in small diameter tubes [PDF]

open access: yes, 2007
Copyright @ 2007 RT Edwards Inc.Boiling heat transfer in small diameter tubes has been experimentally investigated using R134a as the working fluid. The heat transfer periments were conducted with two stainless steel tubes of internal diameter 4.26 mm ...
Huo, Y, Karayiannis, TG, Tian, S
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Numerical Study of the Dynamic Response of Heat and Mass Transfer to Operation Mode Switching of a Unitized Regenerative Fuel Cell

open access: yesEnergies, 2016
Knowledge concerning the complicated changes of mass and heat transfer is desired to improve the performance and durability of unitized regenerative fuel cells (URFCs).
Hong Xiao   +3 more
doaj   +1 more source

Influence of metallic porous microlayer on pressure drop and heat transfer of stainless steel plate heat exchanger [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +2 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Study on the Characteristics of Expander Power Output Used for Offsetting Pumping Work Consumption in Organic Rankine Cycles

open access: yesEnergies, 2014
The circulation pump in an organic Rankine cycle (ORC) increases the pressure of the liquid working fluid from low condensing pressure to high evaporating pressure, and the expander utilizes the pressure difference to generate work.
Yu-Ting Wu   +6 more
doaj   +1 more source

Heat transfer device [PDF]

open access: yes, 1976
An improved heat transfer device particularly suited for use as an evaporator plate in a diffusion cloud chamber. The device is characterized by a pair of mutually spaced heat transfer plates, each being of a planar configuration, having a pair of ...
Eaton, L. R.
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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