Results 81 to 90 of about 352,836 (265)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Numerical investigation of laminar convective heat transfer of graphene oxide/ethylene glycol-water nanofluids in a horizontal tube

Engineering Science and Technology, an International Journal, 2018
The study provides a numerical analysis of laminar forced convective heat transfer of graphene oxide nanosheets suspended in the mixture of water and ethylene glycol in laminar flow regime using single phase approach in a circular horizontal tube under ...
Muhammad Sajjad, Muhammad Sajid Kamran, Rabia Shaukat, Mudather Ibrahim Mudather Zeinelabdeen   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Artificial Neural Network-Based Heat Transfer Analysis of Sutterby Magnetohydrodynamic Nanofluid with Microorganism Effects

Magnetochemistry
Background: The study of non-Newtonian fluids in thin channels is crucial for advancing technologies in microfluidic systems and targeted industrial coating processes.
Fateh Ali, Mujahid Islam, Farooq Ahmad, Muhammad Usman, Sana Ullah Asif   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Smoldering combustion and blow-off in incense sticks (Effect of wind directions)

Journal of Thermal Science and Technology
The smoldering spread and extinction behavior are significantly impacted by both wind velocity and angle. However, this combined effect has not been extensively quantified.
Pichayaporn VIRIYA-AMORNKIJ, Kazunori KUWANA, Yunzhu QIN, Xinyan HUANG   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Thermal Behaviour of Piggyback-Laid District Heating and District Cooling Pipes

Environmental and Climate Technologies
District heating (DH) and district cooling (DC) networks are key to sustainable urban energy systems. This study investigates thermal interactions between DH and DC pipelines installed in a piggyback configuration within a shared trench using a ...
Dollhopf Stefan, Wieland Aaron, Weidlich Ingo   +2 more
doaj   +1 more source

An analysis of heat transfer in horizontal rotating heat pipes.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B, 1988
The heat transfer performance of coaxial straight heat pipes in high-speed rotation has been analyzed. The parameters are the geometry of the pipe, the kind of working fluid, the mass of the working fluid charged in the pipe, the rotation rate and the heat load.
FUJIOKA, Kazumasa, NAKAYAMA, Wataru
openaire   +2 more sources