Results 51 to 60 of about 4,323,986 (291)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Heat transfer coefficient as parameter describing ability of insulating liquid to heat transfer
E3S Web of Conferences, 2017 The paper presents the results of the measurements of heat transfer coefficient of insulating liquids used in transformers. The coefficient describes an ability of the liquid to heat transport.
Nadolny Zbigniew +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Zhileng xuebao, 2016 Experiments are performed in rectangular micro-channels (dH =0.293 mm) under the condition of different mass flux and heat flux to evaluate the flow boiling heat transfer characteristics with deionized water and anhydrous ethanol.
Chen Yumin, Liu Dongyao
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
MATEC Web of Conferences, 2018 The work is a part of a thermodynamic analysis of a finned cross-flow heat exchanger of the liquid-gas type. The heat transfer coefficients on the liquid and the gas side and the area of the heat transfer are the main parameters describing such a device.
Bury Tomasz +1 more
doaj +1 more source
Frontiers in Energy Research, 2020 The study of the commonness and differences of natural circulation of different liquid metals plays an important role in improving the safety of reactors.
Feng Xiang +14 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Heat Transfer Characteristics during Condensation of R134a inside Micro-fin Tubes
Zhileng xuebao, 2018 Experimental study of R134aduring condensation heat transfer inside the micro-fin tube for the condensation temperatures of 35 ℃、40 ℃ and 45 ℃ was made.
Li Qingpu +4 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source