Results 131 to 140 of about 3,847,286 (297)
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Assessment of downhole heat exchangers in Puna district, Hawaii
, 2007 "Downhole heat exchangers (DHEs) have the potential for use in direct (non-electric) applications of geothermal energy. Their benefit is that no groundwater is extracted from wells.
Geo-Heat Center, Oregon Institute of Technology
core +2 more sources
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Thermodynamic decoupling in the deep-strong coupling regime
JPhys PhotonicsIn the deep-strong coupling (DSC) regime, the interaction between light and matter exceeds their bare frequencies, leading to an effective decoupling.
S Palafox +3 more
doaj +1 more source
Internally heated convection with rotation: bounds on heat transport
Journal of Fluid MechanicsThis work investigates heat transport in rotating internally heated convection, for a horizontally periodic fluid between parallel plates under no-slip and isothermal boundary conditions. The main results are the proof of lower bounds on the mean temperature, $\overline {{\langle {T} \rangle }}$ , and the heat flux out of the
openaire +4 more sources
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Nuclear FusionA large database of more than 1000 individual cryogenic hydrogen pellets injected into Wendelstein 7-X for plasma fueling was analyzed to improve the understanding of the three phases of the process: the ablation, deposition and transport of the pellet ...
H. Damm +16 more
doaj +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Scaling of Latitude‐Dependent Heat Transport in Geostrophic Convection
Geophysical Research LettersLatitudinal variations in heat transport shape the thermal and magnetic evolution of rapidly rotating planets, stars, and icy moons. Although global simulations have revealed strong equatorial–polar contrasts, a predictive scaling theory has been lacking.
Veeraraghavan Kannan +2 more
doaj +1 more source