Results 61 to 70 of about 352,570 (269)

The Bending of Three-Layer Elastic Core with Variable Stiff Shell

Механика машин, механизмов и материалов, 2008
The bending of three-layer elastic core with variable thickness of one of two stiff shells is considered. To describe kinematics of asymmetrical over thickness pack of the core the hypotheses of the broken normal are accepted.
Yu.M. Pleskachevsky, E.E. Starovoytova
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Vibration of Circular Metal-Polymeric Plates on an Elastic Foundation under Heat Stroke

Механика машин, механизмов и материалов, 2009
The axisymmetrical vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation ander heat stroke are explored. For the kinematics description asymmetrical on the thickness of package accepted hypothesises broken normal ...
Yu.M. Pleskachevsky , V.D. Kubenko , E.I. Starovoitov , D.V. Leonenko   +3 more
doaj  

Intensification of Heat Transport from the Furnace to Heat Accumulator through a Phase Change

Communications, 2017
In the article the authors analyse the process of heat transport from the furnace to a heat accumulator through a phase change of a heat carrier (working substance), design a construction and describe measurements done on experimental equipment.
Milan Malcho, Stanislav Gavlas, Peter Hrabovsky, Roman Banovcan, Tomas Puchor, Lukasz Orman, Tadeas Ochodek   +6 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

The Heat Carrier Flow Control in Heat Transport Systems

Bulletin of the South Ural State University. Ser. Computer Technologies, Automatic Control & Radioelectronics, 2016
Панферов Владимир Иванович, д-р техн. наук, профессор, зав. кафедрой теплогазоснабжения и вентиляции, Южно-Уральский государственный университет, г. Челябинск; tgsiv@mail.ru. Панферов Сергей Владимирович, канд. техн. наук, доцент кафедры теплогазоснабжения и вентиляции, Южно-Уральский государственный университет, г. Челябинск; tgsiv@mail.ru.
PANFEROV V.I., PANFEROV S.V.
openaire   +4 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Modeling of Mechanical Interaction of Reinforcement with Matrix Composite

Механика машин, механизмов и материалов, 2009
There is solved the problem on determination influence of contact parameters between composite reinforcement and a matrix on strengthening and stiffness of a supporting structure. It is executed on a finite element modelling basis.
Yu.M. Pleskachevsky , A.O. Shimanovsky , O.I. Yakubovich , G.M. Kuziomkina   +3 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source