Results 81 to 90 of about 3,860,978 (296)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Heat Carrier Flow Control in Heat Transport Systems
Bulletin of the South Ural State University. Ser. Computer Technologies, Automatic Control & Radioelectronics, 2016 Панферов Владимир Иванович, д-р техн. наук, профессор, зав. кафедрой теплогазоснабжения и вентиляции, Южно-Уральский государственный университет, г. Челябинск; tgsiv@mail.ru. Панферов Сергей Владимирович, канд. техн. наук, доцент кафедры теплогазоснабжения и вентиляции, Южно-Уральский государственный университет, г. Челябинск; tgsiv@mail.ru.
PANFEROV V.I., PANFEROV S.V.
openaire +4 more sources
Modeling of Mechanical Interaction of Reinforcement with Matrix Composite
Механика машин, механизмов и материалов, 2009 There is solved the problem on determination influence of contact parameters between composite reinforcement and a matrix on strengthening and stiffness of a supporting structure. It is executed on a finite element modelling basis.
Yu.M. Pleskachevsky +3 more
doaj
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Dynamics of Circular Metal-Polymeric Plates on an Elastic Foundation. Part I. FREE VIBRATIONS
Механика машин, механизмов и материалов, 2008 The axisymmetrical free vibrations of elastic circular three-layer metal-polymeric plate on en elastic foundation are explored. Reaction of foundation was described on the base of Winkler’s model.
Yu.M. Pleskatshevsky +2 more
doaj
Heat Content Anomaly and Decay of Warm‐Core Rings: the Case of the Gulf of Mexico
Geophysical Research Letters, 2020 In this study, we harness the 25‐year satellite‐altimeter record, in concert with a vast array of in situ measurements, to estimate the heat content anomaly of 32 warm‐core rings in the Gulf of Mexico (GoM).
Thomas Meunier +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Transport outlook 2010: The potential for innovation [PDF]
, 2010 This paper provides evidence on and discussion of recent developments in global transport markets and analyzes what policies look most promising for stabilizing CO2-emissions from light-duty vehicles.
International Transport Forum, OECD
core +1 more source
Modeling the Operating Conditions of Electric Power Systems Feeding DC and AC Traction Substations
EnergiesThis paper presents the findings of the research aimed at developing computer models to determine the operating conditions in electric power systems (EPSs) feeding DC and AC railway substations.
Iliya K. Iliev +6 more
doaj +1 more source
Entropy, 2019 In this work, entropy generation analysis is applied to characterize and optimize a turbulent impinging jet on a heated solid surface. In particular, the influence of plate inclinations and Reynolds numbers on the turbulent heat and fluid flow properties
Florian Ries +4 more
doaj +1 more source