Results 101 to 110 of about 3,847,286 (297)

Heat current control in trapped Bose–Einstein Condensates

New Journal of Physics, 2019
We investigate the heat transport and the control of heat current among two spatially separated trapped Bose–Einstein Condensates (BECs), each of them at a different temperature.
C Charalambous, M A Garcia-March, M Mehboudi, M Lewenstein   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Atlantic Meridional Overturning Circulation slowdown cooled the subtropical ocean [PDF]

, 2013
Observations show that the upper 2 km of the subtropical North Atlantic Ocean cooled throughout 2010 and remained cold until at least December 2011. We show that these cold anomalies are partly driven by anomalous air-sea exchange during the cold winters
Christopher D. Roberts, Johns, William E., David A. Smeed, Darren Rayner, Palmer, Matthew D, McCarthy, Gerard, Smeed, David A, Palmer, Matthew D., Smeed, David A., Roberts, Christopher D., Hobbs, Will, Frajka‐Williams, Eleanor, Will Hobbs, Eleanor Frajka‐Williams, Matthew D. Palmer, Gerard McCarthy, Stuart A. Cunningham, Johns, William E, Rayner, Darren, Roberts, Christopher D, William E. Johns, Cunningham, Stuart A, Cunningham, Stuart A., Frajka-Williams, Eleanor   +23 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Analytical considerations of flow boiling heat transfer in metal-foam filled tubes [PDF]

, 2012
Flow boiling in metal-foam filled tube was analytically investigated based on a modified microstructure model, an original boiling heat transfer model and fin analysis for metal foams.
Zhao, Changying, Tian, Y. (Yuan), Du, Y. P., Qu, Z. G.   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

DEVELOPMENT OF TECHNOLOGY FOR APPLICATION OF PLASMA COMPOSITE COATINGS BASED ON ZIRCONIUM DIOXIDE FOR SPACECRAFT SYSTEMS

Наука и техника, 2015
The paper presents investigation results pertaining to the influence of such parameters as plasma jet (current, spraying distance, expenditure of plasma-forming gas – nitrogen), fraction composition of an initial powder and cooling rate with compressed ...
F. I., Panteleenko, V. A. Okovity, O. G. Devoino, V. M. Astashinsky, V. V. Okovity, S. В. Sobolewski   +5 more
doaj  

Experimental determination of natural convection heat transfer coefficients in an attic shaped enclosure [PDF]

, 2010
Heat transfer by natural convection in triangular enclosures is an area of significant importance in applications such as the design of greenhouses, attics and solar water heaters.
Carson, James K., Duke, Mike, Anderson, Timothy Nicholas   +2 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source