Results 51 to 60 of about 3,860,978 (296)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Meeting society's transport needs under tight budgets [PDF]
In the aftermath of the 2008 financial crisis, both the private and public sectors face stringent constraints in funding for transport infrastructure investment and transport services.
International Transport Forum, OECD
core +1 more source
Loss of sea ice during winter north of Svalbard [PDF]
Sea ice loss in the Arctic Ocean has up to now been strongest during summer. In contrast, the sea ice concentration north of Svalbard has experienced a larger decline during winter since 1979. The trend in winter ice area loss is close to 10% per decade,
Ingrid H. Onarheim +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Charge and heat transport in ionic conductors [PDF]
Transport coefficients relate the off-equilibrium flow of locally conserved quantities, such as charge, energy, and momentum, to gradients of intensive thermodynamic variables in the linear regime.
PEGOLO, PAOLO
core
Heat transport by flow through rough rock fractures: a numerical investigation
International audienceFracture surface topography exhibits long-range spatial correlations resulting in a heterogeneous aperture field. This leads to the formation, within fracture planes, of preferential flow channels controlling flow and transport ...
Méheust, Yves +3 more
core +1 more source
Rewritable printing of ionic liquid nanofilm utilizing focused ion beam induced film wetting
Manipulating liquid flow over open solid substrate at nanoscale is important for printing, sensing, and energy devices. The predominant methods of liquid maneuvering usually involve complicated surface fabrications, while recent attempts employing ...
Haohao Gu +14 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

