Results 101 to 110 of about 9,345 (219)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Internally heated convection with rotation: bounds on heat transport

Journal of Fluid Mechanics
This work investigates heat transport in rotating internally heated convection, for a horizontally periodic fluid between parallel plates under no-slip and isothermal boundary conditions. The main results are the proof of lower bounds on the mean temperature, $\overline {{\langle {T} \rangle }}$ , and the heat flux out of the
openaire   +4 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Core plasma fueling by fast inward particle transport after hydrogen pellet injection in Wendelstein 7-X

Nuclear Fusion
A large database of more than 1000 individual cryogenic hydrogen pellets injected into Wendelstein 7-X for plasma fueling was analyzed to improve the understanding of the three phases of the process: the ablation, deposition and transport of the pellet ...
H. Damm, J. Baldzuhn, R.C. Wolf, T.S. Petersen, J. Schilling, N. Panadero, S.A. Bozhenkov, C. Brandt, K.J. Brunner, G. Fuchert, J. Knauer, A. Langenberg, S. Kwak, N.A. Pablant, E. Pasch, H. Thomsen, the W7-X Team   +16 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Scaling of Latitude‐Dependent Heat Transport in Geostrophic Convection

Geophysical Research Letters
Latitudinal variations in heat transport shape the thermal and magnetic evolution of rapidly rotating planets, stars, and icy moons. Although global simulations have revealed strong equatorial–polar contrasts, a predictive scaling theory has been lacking.
Veeraraghavan Kannan, Varghese Mathai, Xiaojue Zhu   +2 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Observed Subsurface Marine Heatwaves Driven by Subsurface Eddies in the Western Tropical Pacific Ocean

Geophysical Research Letters
Marine heatwaves (MHWs) are extreme warm water events with high impact, but the drivers of subsurface MHWs, particularly the role of subsurface eddies in the occurrence of subsurface MHWs, are unclear yet. Previous studies suggest that surface warm water
Shihan Li, Shijian Hu, Xiangzhou Song
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Pacific Arctic sea ice loss resulting from atmospheric circulation-driven ocean heat transport

Environmental Research Letters
Arctic sea ice is disappearing rapidly, but the melt comes from two different pathways: direct surface warming and the movement of warm water into the Arctic. This study focuses on the latter, i.e.
Yungi Hong, S-Y Simon Wang, Jin-Ho Yoon
doaj   +1 more source