Results 101 to 110 of about 3,101,587 (287)

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Preparation of tobacco pyrolysis liquids in subcritical/supercritical ethanol and their application in the aroma enhancement of heated cigarettes

Frontiers in Chemistry
For the aroma enhancement research of heated cigarettes, it is worth exploring whether tobacco can be pyrolyzed into pyrolysis liquids containing a large number of volatile aroma components.
Xuebin Zhao, Shengchen Zhao, Yongming Xu, Heng Xu, Zhan Zhang, Haiying Tian, Qiang He, Shengtao Ma, Beibei Gao, Chengjie Ma   +9 more
doaj   +1 more source

Proportion, Five‐Year Survival Rate of Laryngeal Cancer and Its Associated Factors Among Head and Neck Cancer Patients in Tanzania

Eye &ENT Research, EarlyView.
ABSTRACT Background Laryngeal cancer carries a significant global burden, with substantial morbidity and mortality, and is increasing globally, with 95%–98% being squamous cell carcinoma. Males are more affected than females, with peak cases occurring between 60 and 80 years of age.
Amenye Adili, Furaha Serventi, Baraka M. Musimu, Mica Magembe, Orest Tarimo, Geofrey Ikelesho, Salum Kalonge, Leonard Kiboko, Queen Godfrey Tarimo, Desderius C. Chussi   +9 more
wiley   +1 more source

The Moderating Effect of Physical Activity Between IQOS Smoking and Ventricular Repolarization Parameters in Lebanese University Students

Health Science Reports
Background Cigarette smoking is a major modifiable risk factor for cardiovascular morbidity and sudden cardiac death, in part through abnormalities in ventricular repolarization.
Jean Khalil, Lucia Helou, Maria Ibrahim, Nicolas Nakhle, Mikhael Kossaify, Talal Harb, Souheil Hallit   +6 more
doaj   +1 more source

Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York

ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.
Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta, Ellen Brinza, Prateeti Khazanie, Pamela N. Peterson, P Michael Ho, David P. Kao   +5 more
wiley   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

Flavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang, Wei Meng, Renzhong Wang, Huijun Du   +3 more
wiley   +1 more source

Evapotranspiration Estimation and Irrigation Performance Assessment Using Remote Sensing: A Case Study of the Ergani Dam Irrigation System (Turkey)

Irrigation and Drainage, EarlyView.
ABSTRACT Efficient water resource management is critical for sustainable agriculture, with evapotranspiration (ET) serving as a key parameter. Remote sensing (RS) techniques offer cost‐effective approaches for ET estimation and irrigation performance assessment in extensive agricultural systems.
Kivanç Hayri Doganay, Bekir Sitki Karatas   +1 more
wiley   +1 more source

Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background E‐cigarettes contribute to endothelial dysfunction, a known cause of systemic atherosclerotic disease that cannot be adequately characterized by a single physiological parameter measured at a single vascular bed. Purpose/Hypothesis Quantify and compare acute effects of smoking or vaping with tobacco cigarettes (t‐cigs), nicotinized ...
Marianne Nabbout, Mahdie Hosseini, Harris Quach, Michael C. Langham, Alessandra S. Caporale, Wensheng Guo, Kathryn Jaroszynski, Frank T. Leone, Andrew A. Strasser, Felix W. Wehrli   +9 more
wiley   +1 more source

Heated tobacco products

Heated tobacco products (HTPs) are nicotine-delivery devices that heat tobacco below 350 °C and have gained popularity since their introduction on the European market, especially among smokers, ex-smokers, and young never-smokers. Sales surged by over 1000% between 2018 and 2020 in several European countries.
openaire   +2 more sources

Patterns of Use of Heated Tobacco Products: A Comprehensive Systematic Review

Journal of Epidemiology
Relative or absolute safety of heated tobacco products (HTPs) remains unknown, while independent literature suggests that these products do not favor tobacco control. We conducted a comprehensive systematic review and meta-analysis to evaluate HTP usage patterns and the effect of HTP use on conventional tobacco smoking (use transitions).We used Pubmed ...
Scala, Marco, Dallera, Giulia, Gorini, Giuseppe, Achille, Jérémie, Havermans, Anne, Neto, Clara, Odone, Anna, Smits, Luc, Zambon, Antonella, Lugo, Alessandra, Gallus, Silvano   +10 more
openaire   +7 more sources