Detection and decontamination of Mycobacterium chimaera and other non-tuberculosis mycobacteria in heater–cooler devices used in cardiopulmonary bypass: a Manufacturer and National guidelines summary, and a potential resolution to the problem requiring further investigation [PDF]
Since 2011, invasive infections due to Mycobacterium chimaera have been diagnosed in patients with previous cardiac surgery. The use of heating/cooling devices (heater–cooler units), necessary to regulate the blood temperature in extra-corporeal ...
Beatrice Casini +2 more
exaly +7 more sources
Mycobacterium chimaera infections among cardiothoracic surgery patients associated with heater-cooler devices—Kansas and California, 2019 [PDF]
Background: In 2015, an international outbreak of Mycobacterium chimaera infections among patients undergoing cardiothoracic surgeries was associated with exposure to contaminated LivaNova 3T heater-cooler devices (HCDs).
Kerui Xu +13 more
semanticscholar +6 more sources
Persistence of Legionella in Routinely Disinfected Heater-Cooler Units and Heater Units assessed by Propidium Monoazide qPCR [PDF]
Background: Evidence to date indicates that heater–cooler units (HCUs) and heater units (HUs) can generate potentially infectious aerosols containing a range of opportunistic pathogens such as Mycobacterium chimaera, other non-tuberculous mycobacterial ...
Savina Ditommaso +4 more
doaj +3 more sources
The Global Outbreak of M. chimaera Infection Following Cardiac Surgery: Another Piece of the Puzzle [PDF]
Invasive cases of Mycobacterium chimaera have been found in Europe, and beyond, and have been associated with the use of heater–cooler units necessary to regulate the temperature of blood in extracorporeal circulation during cardiac surgery, mostly due ...
Savina Ditommaso +5 more
doaj +3 more sources
Classic Pages of the Journal of Extracorporeal Technology: Heater-Cooler Devices as a Conceivable Source of Infection. [PDF]
Weitkemper et al. (1) concisely stated the 2002 issues surrounding the use of tap water in heater-cooler devices (the U.S. Food and Drug Administration [FDA] is using “HCDs”) in the operating room environment.
Riley JB.
europepmc +4 more sources
Longitudinal increase in the detection rate of Mycobacterium chimaera in heater-cooler device-derived water samples. [PDF]
Colonization with Mycobacterium chimaera and other nontuberculous mycobacteria (NTM) has been reported for heater-cooler devices (HCD) produced by several manufacturers.
P. Schreiber +7 more
semanticscholar +6 more sources
Background: From 2013 onwards, a large outbreak of Mycobacterium chimaera (MC) invasive infection, which was correlated with the use of contaminated heater–cooler units (HCUs) during open chest surgery, was reported from all over the world.
Angela Cannas +11 more
doaj +3 more sources
Mycobacterium chimaera Outbreak Associated With Heater-Cooler Devices: Piecing the Puzzle Together [PDF]
An outbreak of invasive Mycobacterium chimaera infections associated with heater-cooler devices (HCDs) has now affected patients in several countries on different continents.
R. Sommerstein +6 more
semanticscholar +10 more sources
Nontuberculous Mycobacterium Infections Associated With Heater-Cooler Devices [PDF]
Disseminated nontuberculous mycobacterium infections have occurred following surgical procedures involving extracorporeal circulation; contaminated water from heater-cooler devices (HCDs) has been implicated as the source. The purpose of this review was to evaluate the public health concern and to educate physicians who care for this patient population.
Keith B Allen +2 more
exaly +4 more sources
Notes from the Field:Mycobacterium chimaeraContamination of Heater-Cooler Devices Used in Cardiac Surgery—United States [PDF]
In the spring of 2015, investigators in Switzerland reported a cluster of six patients with invasive infection with Mycobacterium chimaera, a species of nontuberculous mycobacterium ubiquitous in soil and water. The infected patients had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation (1).
Kiran M Perkins, Charles L․ Daley
exaly +4 more sources

