Results 51 to 60 of about 549,280 (285)

Heating and cooling degree-days vs climate change in years 1979-2021. Evidence from the European Union and Norway

Economics and Environment
Energy consumption depends strongly on weather conditions. Thus, to formulate energy-related policy goals, it is crucial to monitor changes related to the heating degree days (HDD) and cooling degree days (CDD) – widely applied indicators of climate ...
Sylwia Pangsy-Kania, Justyna Biegańska, Floros Flouros, Aneta Sokół   +3 more
doaj   +1 more source

Building energy model validation and estimation using heating and cooling degree days (HDD–CDD) based on accurate base temperature

Energy Science & Engineering, 2022
A great deal of energy used in buildings is directed toward heating, ventilation, and air‐conditioning (HVAC). The key procedure in reducing heating and cooling loads is the creation of a baseline model that represents a theoretical version of the ...
Mahmood Mehregan, Alireza Naminezhad, Sajjad Vakili, Mostafa Delpisheh   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Forecasting Day-Ahead Electricity Demand in Australia Using a CNN-LSTM Model with an Attention Mechanism

Applied Sciences
Accurate energy demand forecasting is vital for optimizing resource allocation and energy efficiency. Despite advancements in various prediction models, existing approaches often struggle to capture the complex, nonlinear relationships between ...
Laial Alsmadi, Gang Lei, Li Li
doaj   +1 more source

Coupled TRNSYS-CFD simulations evaluating the performance of PCM plate heat exchangers in an Airport Terminal building displacement conditioning system [PDF]

, 2013
This is the post-print version of the Article. The official published version can be accessed from the link below. Copyright @ 2013 Elsevier.This paper reports on the energy performance evaluation of a displacement ventilation (DV) system in an airport ...
Alauzet, Arce, Arias, Arkar, ASHRAE Standard 55-2004, Auliciems, Awbi, B.L. Gowreesunker, Bolatturk, Bryn, Chartered Institute of Building Services Engineering, Chartered Institute of Building Services Engineering, Crawley, Day, Dolado, Fan, Fanger, Gebremedhin, Goodfellow, Gousseau, Gowreesunker, Hussain, Idelchik, Kolokotroni, Leenknegt, Liu, M. Kolokotroni, Matsuia, Osterman, Parker, Ramponi, Rohdin, S.A. Tassou, Shilei, Simmonds, Simmonds, Susman, Tay, Tye-Gingras, Veluri, Voller, Zalba, Zhai, Zhai, Zhang, Zhang, Zhou   +46 more
core   +1 more source

An 80-year projection of nZEB strategies in extreme climatic conditions of Iraq [PDF]

, 2020
Purpose – The Middle Eastern terrain is expected to encounter unprecedented climatic conditions before the turn of the next century (circa. 80 years), emanating from extreme heat waves that exceed the critical threshold of habitable conditions.
Ahmed, Abdullahi, Al-Saeed, Yahya Wisam Mahdi, Parn, Erika   +2 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

An advanced data analysis method using heating degree-days for estimating the efficiency of buildings in smart cities: A case study of Astana

Results in Engineering
Heating of buildings account for over 40% of global energy consumption and approximately 30% of carbon dioxide emissions. In Kazakhstan, achieving optimal energy efficiency and thermal comfort in residential buildings is particularly challenging due to ...
Ruslan Omirgaliyev, Ayagoz Khamzina, Didar Yedilkhan, Prof, Daniel Friedrich, Nurkhat Zhakiyev   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source