Results 61 to 70 of about 549,280 (285)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
EnergiesIn 2023, residential and commercial sectors together consumed approximately 27.6% of total United States (U.S.) energy, equivalent to about 20.6 quadrillion Btu.
Khaled Bawaneh +2 more
doaj +1 more source
Potential of low-temperature aquifer thermal energy storage (LT-ATES) in Germany
Geothermal Energy, 2022 More than 30% of Germany’s final energy consumption currently results from thermal energy for heating and cooling in the building sector. One possibility to achieve significant greenhouse gas emission savings in space heating and cooling is the ...
Ruben Stemmle +3 more
doaj +1 more source
, 1981 Contained within the 5th Edition (1978 to 1995) of the National Atlas of Canada is a map that shows the annual sum of heating degree days (an indicator of building heating needs). Data for period 1941 to 1970. Companion sheet to Frost-Free Period, Growing Degree-Days, Last Frost in Spring and First Frost in Autumn.
openaire +1 more source
Combined effects on residual strength of a high performance concrete exposed to fire [PDF]
, 2017 Concrete structures exposed to fire suffer from damage, but can remain a certain degree of residual strength. International research has shown that the compressive strength of concrete decreases not only with temperature, but also by the way of cooling ...
Annerel, Emmanuel, Taerwe, Luc
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Assessment the Effects of Climate Change on the Degree of Heating and Cooling Days of Iran [PDF]
جغرافیا و پایداری محیط, 2017 Energy, as one of the most important environmental and economic sustainable development indices, is affected by the conditions of climate change. In addition, they are considered as the main factors of increase or decrease of fuel consumption and energy ...
Hasan Zolfaqari +2 more
doaj
The impact of climate change on air conditioning needs in Andalusia at detailed scales [PDF]
, 2014 Ce travail analyse les variations spatiotemporelles subies par les besoins de climatisation (chauffage et réfrigération) en Andalousie dans le contexte du changement climatique à partir de la comparaison des degrés-jour réfrigération et des degrés-jour ...
Marzo Artigas, Xavier +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source