Results 61 to 70 of about 245,134 (212)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Rapid Fabrication of Flexible Cu@Ag Flake/SAE Composites with Exceptional EMIS and Joule Heating Performance. [PDF]

ACS Omega, 2023
Huang Z, Zhang Y, Wang H, Li Y, Cui J, Wang Y, Liu J, Wu Y.   +7 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Field Study on the Variation and Impact of the "Cold and Wet Island Effect" of Air-Source Heat Pumps under Different Array Scales

Zhileng xuebao
With the expansion of air-source heat pump （ASHP） heating systems， ASHP arrays have become the main arrangement for medium-to large-scale heating projects， and their scales continue to expand with the increased demand for heating.
Liang Shimin, Wang Zhe, Gao Xuefeng, Yan Yueru, Wang Gang, Hu Songtao, Xu Ce   +6 more
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Performance Analysis and Experimental Study of Quasi-two-stage Heat Pump Cycle

Zhileng xuebao
To solve the contradiction between the surplus of low-temperature waste heat resources and the shortage of high-temperature heat demand, this study designed a set of high-temperature heat pump unit based on quasi-two-stage compression.
Sun Wenqian, Huang Guohua, Gu Zaifeng, Du Weiwei, Tang Mingsheng, Wu Wei   +5 more
doaj  

Impact of parylene coating on heating performance of intravenous fluid warmer: a bench study. [PDF]

BMC Anesthesiol, 2022
Bayoro DK, Groepenhoff H, Hoolihan D, Rose EA, Pedro MJ, Waldmann AD.   +5 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Life Cycle Assessment of Different Low-Temperature District Heating Development Scenarios: A Case Study of Municipality in Latvia

Environmental and Climate Technologies, 2019
Sustainable heating solutions involving renewable energy sources and low supply/return temperatures for district heating are evolving. Low temperature use in district heating allows reducing the heating operation costs significantly and at the same time ...
Feofilovs Maksims, Pakere Ieva, Romagnoli Francesco   +2 more
doaj   +1 more source

Heating performance of a laboratory pilot-plant combining heat exchanger and air scrubber for animal houses. [PDF]

Sci Rep, 2021
Krommweh MS, Büscher W.
europepmc   +1 more source